Chinese Journal of Tissue Engineering Research ›› 2010, Vol. 14 ›› Issue (9): 1653-1657.doi: 10.3969/j.issn.1673-8225.2010.09.031

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Noninvasive gastric motility measurement and evaluation by bioimpedance

Ren Chao-shi1, Li Zhang-yong1, Wang Wei1, Zhao Shu2, Deng Juan2   

  1. 1College of Bioinformation, Chongqing University of Posts and Telecommunications, Chongqing   400065, China;
    2Institute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin   300192, China
  • Online:2010-02-26 Published:2010-02-26
  • About author:Ren Chao-shi, Professor, Investigator, Doctoral supervisor, College of Bioinformation, Chongqing University of Posts and Telecommunications, Chongqing 400065, China renbme@163.com
  • Supported by:

    the National Natural Science Foundation of China, No. 60471041, 60901045*

Abstract:

BACKGROUND: Bioimpedance method can be used to extract physiology and pathology information relative to the gastric motility states, to investigate the courses of contraction, peristalsis, transmission and emptying of the stomach, to measure and evaluate gastric motility function. However, early studies mainly focused on the emptying of the stomach, and few studies on evaluation of gastric motility by extracting gastric motility information.
OBJECTIVE: To understand the gastric motility from electricity-mechanism composite concept and to establish a noninvasive, convenience measurement method of gastric motility impedance.
METHODS: Based on the characters of gastric motility impedance signal, a measurement method of impedance gastric motility is introduced. Some foundation experiments about the gastric emptying measurement, the gastric motility compare between fasting and repast, the gastric motility comparison of healthy volunteers during different periods and some medicine effects on gastric motility have carried out. The gastric motility measurement of the patients with functional dyspepsia and gastric motility evaluation for the patients with erosive gastritis had been reported.
RESULTS AND CONCLUSION: Using electrical bioimpedance method, according to the electrical property of the stomach tissue or the food in stomach and the change rules of the property, the physiology and pathology information relative to the gastric motility states can be extracted, the courses of contraction, peristalsis, transmission and emptying of the stomach can be investigated and noninvasive measure and evaluation of gastric motility function can be realized.

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