Abstract:

BACKGROUND: Ca ²⁺ acts as an essential intracellular signal in the process of excitation-contraction coupling in inner skeletal muscles. The excitatin-contraction coupling is closely associated with intracellular calcium homeostasis in skeletal muscles.
OBJECTIVE: To review the research progresses on the mechanisms of calcium controlling in skeletal muscles and the interrelationship between intracellular calcium homeostasis and exercises.
METHODS: A computer online search was performed to find papers published between 1980 and 2010 in databases of CNKI, Duxiu academic search, Elsevier SD and Springer Link. Documents concerning skeletal muscle excitatin-contraction coupling and calcium homeostasis were included to analyze the interrelationship between intracellular calcium homeostasis and exercises.
RESULTS AND CONCLUSION: A total of 43 literatures were included in this study. There were closely relationships between intracellular calcium homeostasis and exercises. However, controlling mechanisms of intracellular calcium homeostasis remain poorly understood. The precise relationship between sports and calcium homeostasis needs further explored. How to exercise properly, what are the pathogenesis of sports fatigue, and how to prevent and anti-sports fatigue or muscle injury are the research focuses.