Abstract:

BACKGROUND: Patients with deep burn wounds undergoing heterogeneous decellularized dermal matrix graft need to experience a long period of convalescence. During this period, patients are likely to develop pigmentation, scar contracture, looks damage, dysfunction and other complications, so there are relatively high requirements for postoperative functional rehabilitation.
OBJECTIVE: To discuss the role of functional rehabilitation exercises after the heterogeneous decellularized dermal matrix graft in repair of deep burn wounds.
METHODS: Totally 72 patients with deep II degree burn were randomly divided into treatment and control groups (n=36/group), and all subjected to heterogeneous decellularized dermal matrix graft treatment. At the day after treatment, patients in the treatment group were subjected to positively postoperative functional rehabilitation exercises; patients in the control group only received psychological assessment and data collection. After 2 months of functional rehabilitation exercises, the assessment results on degree of dermal swelling, pain, serum levels of inflammatory cytokines and quality of life of patients in these two groups were compared.
RESULTS AND CONCLUSION: There was no significant difference in the degree of dermal swelling of patients between these two groups (P > 0.05). The degree of pain, levels of tumor necrosis factor α and interleukin-6 levels were significantly lower in the treatment group than in the control group (P < 0.05), and the scores of each dimension were significantly higher than in the control group (P < 0.05). These results demonstrate that postoperative functional rehabilitation exercises after the heterogeneous decellularized dermal matrix graft in repair of deep burn wounds can relieve pain, inhibit inflammatory reactions and promote the recovery of the patient’s body function.