Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (52): 9766-9770.doi: 10.3969/j.issn.2095-4344.2012.52.015

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Complications of osteoporotic vertebral compression fractures treated with bone cement enhancement technology

Li Da-gang, Su Pei-ji, Chen Gan-feng, Chen Shi-zhong, Gao Heng   

  1. First Department of Orthopedics, Hospital of Traditional Chinese Medicine of Zhongshan, Guangzhou University of Traditional Chinese Medicine, Zhongshan 528402, Guangdong Province, China
  • Received:2012-05-17 Revised:2012-07-08 Online:2012-12-23 Published:2012-12-23
  • About author:Li Da-gang☆, Doctor, Attending physician, First Department of Orthopedics, Hospital of Traditional Chinese Medicine of Zhongshan, Guangzhou University of Traditional Chinese Medicine, Zhongshan 528402, Guangdong Province, China zsortho@163.com

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Abstract:

BACKGROUND: Both vertebroplasty and kyphoplasty are minimally invasive surgeries for the treatment of osteoporotic vertebral compression fractures.
OBJECTIVE: To evaluate the safety of vertebroplasty and kyphoplasty for the treatment of osteoporotic vertebral compression fractures.
METHODS: A search was conducted using Medline database, EMBASE database, CNKI database, Wanfang database and VIP database from January 1990 to January 2012 for the articles on the complications after osteoporotic vertebral compression fractures treated with vertebroplasty and kyphoplasty.
RESULTS AND CONCLUSION: A total of 62 studies and 8 993 patients met the inclusion criteria. There was no significant difference of puncture complications and other complications between vertebroplasty and kyphoplasty. The rates of cement leakage and new vertebral compression fractures of vertebroplasty were higher than those of kyphoplasty (P=0.000 06, P=0.02); there was no significant difference of adjacent vertebral fractures rate between vertebroplasty and kyphoplasty. The results demonstrate that vertebroplasty and kyphoplasty are two minimally invasive methods for the treatment of osteoporotic vertebral compression fractures. There was no significant difference of adjacent vertebral fractures rate, puncture complications and other complications between vertebroplasty and kyphoplasty, but the cement leakage and new vertebral compression fractures of kyphoplasty were lower than those of vertebroplasty. So, future prospective studies with a large number of patients are needed for the systematic review.

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