Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (35): 6550-6554.doi: 10.3969/j.issn.2095-4344.2012.35.018

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Posterior pedicle screw fixation combined with nanotechnology bone graft for the treatment of thoracolumbar fracture

Huang Qi-kai, Li Ming, Hu Wen   

  1. Department of Orthopedics, Changhai Hospital, Second Military Medical University of Chiese PLA, Shanghai 200433, China
  • Received:2012-01-04 Revised:2012-02-11 Online:2012-08-26 Published:2012-08-26
  • Contact: Li Ming, Professor, Chief physician, Doctoral supervisor, Department of Orthopedics, Changhai Hospital, Second Military Medical University of Chiese PLA, Shanghai 200433, China limingch@21.com
  • About author:Huang Qi-kai★, Studying for master’s degree, Department of Orthopedics, Changhai Hospital, Second Military Medical University of Chiese PLA, Shanghai 200433, China huangqikai@126.com

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Abstract:

BACKGROUND: Nanotechnology bone has the advantages of osteoinductive activity and excellent osteogenic property, and it can be shaping with less adverse reactions.
OBJECTIVE: To observe the effect of posterior pedicle screw fixation combined with nanotechnology bone graft on the treatment of thoracolumbar fractures.
METHODS: Forty-eight thoracolumbar fracture patients were treated with posterior pedicle screw fixation combined with nanotechnology bone graft within 3 days after in hospital, the Cobb angel, the anterior vertebral height and bone healing before and after treatment were analyzed and compared.
RESULTS AND CONCLUSION: All patients were followed-up for over 9 months. At 7 days after nanotechnology bone implantation and the last follow-up, the Cobb angel and the anterior vertebral height were significantly improved compared with the pre-operation (P < 0.05), while there was no significant difference of the indexes (P > 0.05). All injured vertebral bone was healed well. For the treatment of thoracolumbar fractures, posterior pedicle screw fixation combined with nanotechnology bone graft has a good effect in maintaining the stability and the correction efficiency of reconstructed spine with high fusion rate and short healing time.

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