Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (4): 571-574.doi: 10.3969/j.issn.1673-8225.2011.04.001

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Total knee arthroplasty for osteoarthritis patients: A multi-central randomized controlled trial

Wang Guo-wei1, Sun Shui2, Lin Yong-jie1, Chen Ji-ying3, Zhou Yong-gang3, Shi En-dong1   

  1. 1Shandong Jiaotong Hospital, Jinan  250031, Shandong Province, China
    2Shandong Provincial Hospital, Jinan  250100, Shandong Province, China
    3Department of Joint Surgery, General Hospital of Chinese PLA, Beijing  100037, China
  • Received:2010-07-19 Revised:2010-12-25 Online:2011-01-22 Published:2011-01-22
  • About author:Wang Guo-wei★, Master, Attending physician, Shandong Jiaotong Hospital, Jinan 250031, Shandong Province, China alexrt@126.com
  • Supported by:

    a grant from Communication Department of Shandong Province, No. 2008Y023(6)*

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Abstract:

BACKGROUND: Total knee arthroplasty (TKA) can be performed for osteoarthritis patients, aged more than 60 years, with joint pain, dysfunction and joint deformity.
OBJECTIVE: To compare differences in early joint functional recovery between three kinds of TKA surgery, i.e. TKA, minimally invasive surgery (MIS)-TKA and MIS-quadriceps sparing (QS)-TKA. 
METHODS: 120 osteoarthritis patients were selected from Beijing 301 Hospital, Shandong Provincial Hospital, and Shandong Jiaotong Hospital, including 42 undergoing traditional TKA, 42 MIS-TKA and 36 MIS-QS TKA. Each knee was rated according to the Hospital of Special Surgery (HSS) scoring system at 2, 6, and 12 weeks post-operatively. Range of motion was detected.
RESULTS AND CONCLUSION: The operation time was longer in MIS-TKA and MIS-QS TKA groups compared with TKA group (P < 0.01), but the bleeding amount was less (P < 0.01). There was no obvious difference between MIS-TKA and MIS-QS TKA groups (P > 0.05). Range of motion and HSS scores of MIS-TKA and MIS-QS TKA groups were superior over traditional TKA at postoperative 2 weeks (P < 0.01), but there was no prominent difference of ROM between MIS-TKA and MIS-QS TKA groups (P > 0.05). The HSS scores were significantly greater in MIS-QS TKA compared with MIS-TKA (P < 0.01). At 6 and 12 weeks, there were no significant differences in HSS scores or range of motion among three groups (P > 0.05). Compared with traditional TKA, MIS-TKA and MIS-QS TKA showed less bleeding amount, less injury to the quadriceps, and this could contribute to the earlier recovery of the patients.

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