Chinese Journal of Tissue Engineering Research ›› 2010, Vol. 14 ›› Issue (47): 8873-8876.doi: 10.3969/j.issn.1673-8225.2010.47.033

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Tissue engineering scaffold materials repair sports cartilage injury

Wang Yong-sheng   

  1. Human Body Science Laboratory, College of Physical Education, Henan Polytechnic University, Jiaozuo   454000, Henan Province, China
  • Online:2010-11-19 Published:2010-11-19
  • About author:Wang Yong-sheng★, Master, Human Body Science Laboratory, College of Physical Education, Henan Polytechnic University, Jiaozuo 454000, Henan Province, China sqh@hpu.edu.cn

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Abstract:

OBJECTIVE: To investigate the factors and characteristics of sports cartilage injury, to classify and summarize the selection and application of artificial biomaterial scaffolds in the repair process.
METHODS: An online search of PubMed database (http://www.ncbi.nlm.nih.gov/PubMed) and CNKI database (www.cnki.net/ index.htm) was performed by screening the titles and abstracts with the key words of “Cartilage, Damage, Biological Materials, Support, Treatment” in English and in Chinese. Articles related to the treatment, materials science characteristics, biocompatibility and application effect of cartilage scaffolds were selected, these recently published or published in the authority journals were preferred in the same field, finally 26 articles were included in the analysis.
RESULTS: Over half a century, the selection and design of cartilage tissue engineering scaffold materials have developed from natural materials, synthetic materials, and other single materials to composite materials. In addition, gene technology, nano-materials and modified technology may provide greater potential and ensure for the healing and rehabilitation of cartilage injury.
CONCLUSION: The majority of cartilage injury is caused by sudden violence, and the cartilage cannot repair itself after injury, so cartilage injury is difficult to cure using conventional therapies. With the emergence of tissue engineering, tissue engineering technologies have been gradually applied to cartilage rehabilitation and achieved great success, in particularly the selection and development of cartilage scaffold materials. Single natural materials and synthetic materials have many disadvantages, so the major future direction of scaffold materials research is compound materials, biomimetic materials, and modified materials. With the rapid development and integration of tissue engineering, biological engineering technology and nanotechnology, new composite technology using a variety of materials and technologies will further meet the needs of both doctors and patients.

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