Discectomy versus interbody fusion for lumbar disc herniation with Modic change: a meta-analysis

doi:10.3969/j.issn.2095-4344.2016.09.019

Abstract

Abstract:

BACKGROUND: At present, a large number of studies have proved that the discectomy and interbody fusion are effective in treatment of lumbar disc herniation. But for the treatment of lumbar disc herniation with Modic change, the advantages and disadvantages of above two kinds of surgical methods are still inconclusive.
OBJECTIVE: To systematically review the effectiveness of discectomy versus interbody fusion in treatment of lumbar disc herniation with Modic change.
METHODS: We searched PubMed, Embase, The Cochrane Library (Issue 2, 2015), CBM, CNKI, VIP and WanFang database for randomized controlled trials on discectomy versus interbody fusion for lumbar disc herniation with Modic change from inception to May 1st, 2015. Clinical outcomes were back pain Visual Analog Scale, leg pain Visual Analog Scale, Oswestry Disability Index, lumbar Japanese Orthopaedic Association score, the number of cases affecting complications, and MacNab criteria. Meta-analysis was performed using RevMan 5.2 software.
RESULTS AND CONCLUSION: Nine randomized controlled trials were included, involving 945 patients. The results of meta-analysis showed that compared with discectomy group, back pain Visual Analog Scale was lower [MD=0.81, 95%CI (0.69, 0.92), P < 0.000 01]; Oswestry Disability Index was lower [MD=2.07, 95%CI (1.62, 2.52), P < 0.000 01]; lumbar Japanese Orthopaedic Association score was higher [MD=-2.32, 95%CI (-4.32, -0.32), P=0.02] in the interbody fusion group. No significant difference in leg pain Visual Analog Scale and MacNab criteria outcomes was detected between both groups. These findings verified that interbody fusion was safer and more effective for lumbar disc herniation with Modic change, compared with discectomy.

中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程

Wang Wen-da, Jin Qi, Ruan Wen-feng, Ping An-song. Discectomy versus interbody fusion for lumbar disc herniation with Modic change: a meta-analysis[J]. Chinese Journal of Tissue Engineering Research, 2016, 20(9): 1345-1352.

Figures/Tables 8

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