Chinese Journal of Tissue Engineering Research ›› 2014, Vol. 18 ›› Issue (43): 7007-7011.doi: 10.3969/j.issn.2095-4344.2014.43.020

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Efficacy of video-assisted thoracoscopic entoiodine pleurodesis on primary spontaneous pneumothorax

Wang Zuo-pei, Wei Hai-tao, Zhang Feng, Zhang Hai-feng, Hu Bao-li   

  1. Second Ward, Department of Thoracic Surgery, Huaihe Hospital of Henan University, Kaifeng 475000, Henan Province, China
  • Received:2014-09-02 Online:2014-10-15 Published:2014-10-15
  • About author:Wang Zuo-pei, Master, Attending physician, Second Ward, Department of Thoracic Surgery, Huaihe Hospital of Henan University, Kaifeng 475000, Henan Province, China

Abstract:

BACKGROUND: Some scholars believe that for primary spontaneous pneumothorax thoracoscopic surgery and intraoperative pleurodesis can effectively reduce the recurrence rate.
OBJECTIVE: To study the reliability and validity of video-assisted thoracoscopic entoiodine pleurodesis for treatment of primary spontaneous pneumothorax.
METHODS: Videothoracoscopy procedures were performed on 64 patients with primary spontaneous pneumothorax, including 46 males and 18 females, with an age ranging from 15 to 30 years. According to the use of pleurodesis, the patients were randomly divided into two groups: experimental group and control group. In the control group, no entoiodine was used; while in the experimental group, entoiodine dipped gauze was used on the visceral pleura. The operation time, intraoperative bleeding, postoperative drainage, postoperative leakage time, postoperative extubation time, postoperative complications and the recurrence rate of pneumothorax within     1 year after operation were compared between two groups.
RESULTS AND CONCLUSION: No significance was found in the operation time, intraoperative bleeding, postoperative leakage time, postoperative extubation time and postoperative complications between the two groups (P > 0.05). Although the experimental group had significantly more postoperative drainage volume than the control group (P < 0.05), there were no consequences of medical intervention. Video-assisted thoracoscopic entoiodine pleurodesis could significantly reduce the recurrence rate of pneumothorax in 1 year after operation  (P < 0.05). The results show that video-assisted thoracoscopic operation with entoiodine is a reliable and effective method to reduce the recurrence of pneumothorax after operation in patients with primary spontaneous pneumothorax.


中国组织工程研究杂志出版内容重点:生物材料;骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性;组织工程


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Key words: thoracoscopes, pleurodesis, pneumothorax

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