Vertebral bodies implanted with biodegradable reticulated balloon and calcium phosphate cement: Changes in the vertebral biomechanics

doi:10.3969/j.issn.2095-4344.2013.51.003

Abstract

Abstract:

BACKGROUND: It has become a focus to look for new vertebral body filling materials which have the biomechanical property, biological activity and low cement leakage rate.
OBJECTIVE: To investigate the biomechanical characters and cement leakage rate of the vertebral bodies implanted with biodegradable reticulated balloon and calcium phosphate.
METHODS: Thirty-two vertebral bodies from pigs were randomly divided to four groups. For A group, 2.5-3.0 mL polymethacrylate cement was injected into the body through a unilateral thoracic pedicle pathway; for B group, 2.5-3.0 mL calcium phosphate cement were injected by the same protocol; for C group, the biodegradable reticulated balloons filled with 2.5-3.0 mL calcium phosphate cement were implanted; D group, including normal vertebral bodies, was designed as controls. Leakage of bone cement was observed in each group. The load-shift curves were recorded by an electronic universal testing machine (SCHENCK RSA-250).
RESULTS AND CONCLUSION: The stiffness and strength of A group were significantly higher than those of D group (P < 0.05), and the stiffness and strength of B group were statistically lower than those of D group (P < 0.05).
The stiffness and strength of C group, otherwise, were similar with those of D group (P > 0.05). Cement leakage rate of C group was lower than that of A or B group (P < 0.05). Vertebral bodies implanted with biodegradable reticulated balloons may lead to similar biomechanical characters as the normal vertebral bodies and reduce the cement leakage rate.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

全文链接：

Key words: biocompatible materials, absorbable implants, calcium phosphates, biomechanics

CLC Number:

R318

Peng Xiang-tao, Liu Xun-wei, Li Min, Zhong Jian, Wei Dai-xu, He Dan-nong, Sun Gang . Vertebral bodies implanted with biodegradable reticulated balloon and calcium phosphate cement: Changes in the vertebral biomechanics[J]. Chinese Journal of Tissue Engineering Research, 2013, 17(51): 8795-8800.

Figures/Tables 5

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