Chinese Journal of Tissue Engineering Research ›› 2013, Vol. 17 ›› Issue (47): 8294-8300.doi: 10.3969/j.issn.2095-4344.2013.47.024

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The use of lightweight versus heavyweight mesh in open methods of inguinal hernia repair: A meta-analysis

Wang Jia-sheng1, Hu Tie-yi2, Chen Yong2, Yang Qiang1, Li Zhong-fu1   

  1. 1Department of General Surgery, Yong Chuan Hospital, Chongqing Medical University, Chongqing  402160, China; 2Department of ICU, People’s Hospital of Dazu District, Chongqing  402360, China
  • Revised:2013-08-29 Online:2013-11-19 Published:2013-11-19
  • Contact: Yang Qiang, Professor, Chief physician, Department of General Surgery, Yong Chuan Hospital, Chongqing Medical University, Chongqing 402160, China yq6903@sohu.com
  • About author:Wang Jia-sheng★, Studying for master’s degree, Department of General Surgery, Yong Chuan Hospital, Chongqing Medical University, Chongqing 402160, China 252824992@qq.com

Abstract:

BACKGROUND: It remains controversial in term of efficacy for the lightweight mesh and heavyweight mesh in inguinal hernia repair.
OBJECTIVE: To compare the clinical therapeutic effects of lightweight mesh and heavyweight mesh in open methods of inguinal hernia repair with Meta-analysis.
METHODS: Comprehensive electronic search strategies were developed using the following electronic databases: PubMed, Cochrane Library, EMBASE, Medline, Ovid, CNKI, VIP, Wanfang and FMJS. The Literature published before February 2013 was searched. The randomized controlled trials about comparing lightweight mesh and heavyweight mesh in open methods of inguinal hernia repair were included. A data-extraction sheet was developed based on the preset standards. The data from eligible studies were pooled using RevMan5.1 software through Meta-analysis.
RESULTS AND CONCLUSION: Eighteen trials with a total of 4 450 hernias met the inclusion criteria. The meta-analysis showed that there was a statistical difference between lightweight mesh group and the heavyweight mesh group on short-term pain [odd ratio (OR)=0.57, 95% confidence interval (CI) (0.43, 0.74),   P < 0.05] and a reduced risk of developing foreign body sensations [OR=0.49, 95% CI (0.35, 0.69), P < 0.05]. No significant differences were found between the two groups in recurrence rate, testicular atrophy, seroma, hematoma, wound infection, urine retention (P > 0.05). According to limited evidence, there are some findings as follows: the lightweight mesh is of feasibility, safety and effectiveness for inguinal hernia repair. Because of the limits of sample and quality, more large-sample and high-quality trials are required to make a definite clinical evidence to use lightweight mesh for inguinal hernia repair.

Key words: biocompatible materials, hernia, inguinal, evidence-based practice

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