Abstract:

BACKGROUND: Various traumas caused lower extremity skin and soft tissue defects are very common and often accompanied by severe blood supply damage and wound infection with high infection rate and not easy to heal.
OBJECTIVE: To systematic review the literatures on the treatment of lower extremity skin and soft tissue infections defect, and to explore the indications, methods and clinical significance of flap transplantation combined with closed negative pressure drainage for repairing lower extremity skin and soft tissue defects combined with the treatment results of 23 patients with lower extremity skin and soft tissue defects treated in Pu Ai Hospital of Wuhan, Tongji Medical College of Huazhong University of Science and Technology.
METHODS: Twenty-three patients with lower extremity skin and soft tissue defects treated in Pu Ai Hospital of Wuhan, Tongji Medical College of Huazhong University of Science and Technology were selected from August 2004 to November 2011, 15 cases in male and 8 cases in female; the age was 17-56 years, average 31.4 years. All the patients were treated with flap transplantation combined with closed negative pressure drainage. The follow-up time was 4-15 months, average 7.3 months, and then the clinical effects were observed. The relative literatures on the lower extremity skin and soft tissue defects were screened and found the similar treatment objects and the same evaluation criteria for comparison.
RESULTS AND CONCLUSION: Among the 23 patients with lower extremity skin and soft tissue defects, the wound infections bacteria including Gram-positive bacteria accounted for 52.2%, Gram-negative bacteria accounted for 47.8% and multi-resistant bacteria accounted for 43.5%. After treated with closed negative pressure drainage, the wound infection was effectively controlled and the growth of wound granulation tissue was good. The wound was healed after flap transplantation. The results showed that flap transplantation combined with closed negative pressure drainage for repairing lower extremity skin and soft tissue defects could shorten wound healing time.