Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (41): 7768-7771.doi: 10.3969/j.issn.2095-4344.2012.41.033

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Role of periodontal ligament stem cells during regeneration of periodontal tissue

Yu Hai-tao, Maimaitili·Gulibaha   

  1. Department of Stomatology, Fifth Affiliated Hospital of Xinjiang Medical University 830054, Urumqi 830011, Xinjiang Uyghur Autonomous Region, China
  • Received:2012-05-20 Revised:2012-07-10 Online:2012-10-07 Published:2012-10-07
  • Contact: Maimaitili·Gulibaha, Master, Chief physician, Department of Stomatology, Fifth Affiliated Hospital of Xinjiang Medical University 830054, Urumqi 830011, Xinjiang Uyghur Autonomous Region, China guli51287@yahoo.com.cn
  • About author:Yu Hai-tao★, Master, Department of Stomatology, Fifth Affiliated Hospital of Xinjiang Medical University 830054, Urumqi 830011, Xinjiang Uyghur Autonomous Region, China yht555@yeah.net

Abstract:

BACKGROUND: It is difficult to regenerate the periodontal tissue because the number of stem cells is not enough and their biological function is insufficient.
OBJECTIVE: To summarize the progress and perspective of periodontal ligament stem cells for the periodontal tissue regeneration in dentistry.
METHODS: The first author searched PubMed database and CNKI database (2000-01/2012-07) for articles regarding isolation, identification, and relevant factors of periodontal ligament stem cells published between January 2000 and July 2012 using the key words of “periodontal ligament stem cells” in English and “periodontal ligament, stem cells” in Chinese. Repetitive articles were excluded, and 26 articles were included in the final analysis.
RESULTS AND CONCLUSION: Using tissue engineering technology, periodontal ligament stem cells were used as the seed cells of periodontal tissue regeneration and transplanted into the defected area after in vitro culture and amplification. Results showed that periodontal ligament stem cells can promote the regeneration of periodontal attachment tissue and shorten the healing period. The study of periodontal ligament stem cells has become a key point in the field of tooth tissue engineering.

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