Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (40): 7480-7485.doi: 10.3969/j.issn.2095-4344.2012.40.014

Previous Articles     Next Articles

Evaluation on opening status of the mechanical heart valve in vitro under pulsatile flow

Chu Yin-ping1, Cheng Jin-lian2, Liu Ai-jun3, Gao Qi-ying1, Zhang Yu1, Zhang Dong1   

  1. 1Department of Cardiac Surgery, Shanxi Provincial People’s Hospital, Taiyuan 030012, Shanxi Province, China
    2First Affiliated Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi Province, China
    3Second Affiliated Hospital of Shanxi Medical University, Taiyuan 03001, Shanxi Province, China
  • Received:2011-12-08 Revised:2012-01-31 Online:2012-09-30 Published:2012-09-30
  • About author:Chu Yin-ping☆, Doctor, Professor, Chief physician, Department of Cardiac Surgery, Shanxi Provincial People’s Hospital, Taiyuan 030012, Shanxi Province, China cypcardio@hotmail.com

Abstract:

BACKGROUND: During the estimation of mechanical heart valve prosthesis, many studies related to cardiac output, regurgitant volume, effective orifice area, pressure differences and shear stresses and flow fields, and cavitation phenomenon.
OBJECTIVE: To carry out visual observation and evaluation on the opening status of the leaflets to three kinds of mechanical artificial heart valve prostheses.
METHODS: The pulsatile flow testing experiments were conducted by installing the testing heart valve prosthesis (US-made CarboMedics bileaflet valve, China-made Jiuling bileaflet valve and C-L tilting disc valve) in the aortic position of the physiological mock flow loop. The testing condition was set at pulse frequency of 75 beats/min and a constant cardiac output of 4 L/min and contraction of the cycle time of under 46.2%, respectively. The opening status of the disc valves in 10 continuous pulse cycles was observed by a high-speed camera installed light above the simulated cycle device of arterial lumen upper part. With self designed image processing software package, a picture of the biggest opening angle of the disc valve was shot and it was used as a datum to calculating its biggest opening area and angle for each valve.
RESULTS AND CONCLUSION: The disc valves fluttering were observed when 25 mm CarboMedics bileaflet valve, 25 mm and 23 mm Jiuling double leaflet disc opened to the maximum angle, but 27 mm C-L disc valve was not. The measurement of disc mouth by different calculating methods showed that actual area mouth provided by manufacturers was the biggest, and that the opening area of disc calculated by Green formula was the second, and that the effective opening area calculated by Gorin formula was the smallest. The opening angle of disc valves that calculated by Triangle Law demonstrated that the opening angle of two disc leaflet was inconsistent and less than the inherent opening angle for Jiuling valves and CarboMedics valves. And the opening angle of C-L valve did not reach its inherent opening angle either. The disc leaflets of the mechanical artificial heart valve did not open synchronously and was fluttering in view, the disc leaflets opened incompleted.

CLC Number: