Abstract:

BACKGROUND: Chronic rejection after kidney transplantation and a variety of transplant nephropathy are the common causes of graft loss function, but, to assess the transplant kidney accurately is often very difficult, and biopsy is still the primary method currently.
OBJECTIVE: To investigate the pathological results to diagnosis and treat of kidney puncturation biopsy for postoperative complications after the renal transplantation.
METHODS: Seventy-two renal allograft biopsies were performed. Pathological diagnosis and classification was performed and the data was analyzed.
RESULTS AND CONCLUSION: Among the 72 cases, 35 cases suffered from acute cell-mediated rejection, 12 cases suffered from acute antibody-mediated rejection, 10 cases suffered from renal allograft acute drug toxicity damage, 6 cases suffered from chronic T cell-mediated rejection, 2 cases suffered from chronic antibody-mediated rejection, 4 cases suffered from acute tubular necrosis, and 3 cases suffered from chronic allograft nephropathy. The coincidence between pathological replacement of nephridial tissue after transplantation and clinical diagnosis before puncturation was more than 75%. There was no visible adverse effect after the renal allograft biopsies. Renal graft biopsy is safe and reliable, which guiding significance to find complications of the kidney impaired after transplantation that are difficult to discover on the basis of clinical dates and to choose a more better treatment prescription.