Abstract:

BACKGROUND: Hyperuricemia is a common complication after renal transplantation, if the hyperuricemia caused uric acid nephrolithiasis can not be treated in a timely manner, it may causes the renal allograft loss function after transplantation.
OBJECTIVE: To investigate the diagnosis and treatment program of uric acid nephrolithiasis after renal transplantation.
METHODS: The data of 19 patients with uric acid nephrolithiasis after renal transplantation were collected for the retrospective summary. All the patients had hyperuricemia, eight patients underwent surgical incision for the stone and received the ureter-bladder re-anastomosis, and 11 patients received the conservative treatment.
RESULTS AND CONCLUSION: Sixteen patients had stone at the transplanted lower ureteral, two cases suffered the renal pelvis stone of transplanted renal and hydronephrosis, one case suffered from renal allograft severe hydronephrosis and the entire section of ureteral stone. After treatment, the function and urine output of 18 patients returned to normal; one patient had renal allograft loss function and renal resection. The patients with elevated blood uric acid after renal transplantation should receive the drugs conservative treatment as soon as possible, once the conservative treatment does not work, we should take the surgery way timely in order to reduce postrenal caused renal allograft loss function.