Abstract:

BACKGROUND: In recent years, percutaneous vertebroplasty as a safe and effective minimally invasive surgery has been widely used in the treatment of osteoporotic compression fractures and vertebral tumor-induced osteolytic bone destruction, and has obtained satisfactory results.
OBJECTIVE: To explore the correlation between bone cement and the curative effect of thoracolumbar vertebral fractures by percutaneous vertebroplasty.
METHODS: The VIP database and PubMed database were used to search the articles related to the clinical research of percutaneous vertebroplasty and bone cement implantation with the key words of “pereutaneous vertebroplasty, PVP, thoracic vertebra, lumbar vertebra, vertebral fracture, bone cement” in Chinese and English, respectively. A total of 22 articles were included to review. Forty cases (56 vertabral bodies) with the pain induced by thoracolumbar vertebral fractures were selected from the Department of Orthopedics, the First Affiliated Hospital of Xinxiang Medical University for the clinical validation. The percutaneous vertebroplasty was completed under the guidance of C-arm X-ray machine. The improvement of pain was observed after surgery, and the occurrence of the complications was analyzed.
RESULTS AND CONCLUSION: At present, the commonly used pereutaneous vertebroplasty bone cement includes polymethyl methacrylate bone cement, calcium phosphate cement and calcium sulfate bone cement. The volume and the composition of bone cement required for the sufficient stability of fracture healing and prevention of pain is remains unclear, but we should try to use small doses of bone cement and make the bone cement evenly distributed. Meanwhile, we should select an appropriate injection method based on different situations of the vertebra in order to prevent the leakage of bone cement and new vertebral fractures. The clinical validation results show that percutaneous vertebroplasty is an effective analgesic method, and postoperative follow-up shows that the analgesic effect and the injection amount of bone cement has no positive correlation, and the pain will not weakened over time.