Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (27): 5127-5130.doi: 10.3969/j.issn.1673-8225.2011.27.043

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Lacrimal film recovery following autologous corneal limbus stem cells transplantation for treatment of primary and recurrent pterygium

Jin Ji, Xu Guo-xu, Zhang Ji, Wei Xiao-hong, Bu Shu-yang, Tang Hua, Ji Xiao-yan   

  1. Department of Ophthalmology, Second Affiliated Hospital of Soochow University, Suzhou 215000, Jiangsu Province, China
  • Received:2011-01-28 Revised:2011-03-13 Online:2011-07-02 Published:2011-07-02
  • Contact: Xu Guo-xu, Chief physician, Master’s supervisor, Department of Ophthalmology, Second Affiliated Hospital of Soochow University, Suzhou 215000, Jiangsu Province, China phacoxu@sohu.com
  • About author:Jin Ji★, Master, Physician, Department of Ophthalmology, Second Affiliated Hospital of Soochow University, Suzhou 215000, Jiangsu Province, China jillking@sohu.com

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Abstract:

BACKGROUND: Previous studies mainly focus on influence of different surgical methods on postoperative lacrimal film recovery.
OBJECTIVE: To investigate the effect of one surgery, pterygium excision and autologous corneal limbus stem cells transplantation, on lacrimal film recovery between primary and recurrent pterygium.
METHODS: A total of 32 cases (38 eyes) of primary pterygium and 28 cases (35 eyes) of recurrent pterygium were selected and all underwent pterygium excision and autologous corneal limbus stem cells transplantation. Questionnaire on dry eye, Schirmer I test and break-up time were performed before, one week and one month after operation.
RESULTS AND CONCLUSION: One week after operation, both groups appeared dryness and shortened break-up time, which was more serious in recurrent pterygium group (P < 0.05); there was no significant difference in Schirmer I test between two groups. One month after operation only recurrent pterygium group appeared dryness and shortened break-up time compared with primary pterygium group, which was nearly recovered (P < 0.05). Results showed that the recovery of tear stability and lacrimal secretion was poorer in recurrent pterygium than in primary pterygium, which partly explains high recurrence rate of recurrent pterygium.

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