Abstract:

BACKGROUND: Medical dressings as covering of the wound can replace damaged skin and play a temporary barrier function in the process of wound healing, and avoid or control wound infection to provide a conductive environment for wound healing. How to fixed quickly, stop bleeding effectively, and reduce or prevent the adverse effect of injured limb blood circulation after hemostasis, the acceleration of wound healing and the reduction of pain is an urgent problem of trauma critical care medicine.
OBJECTIVE: To introduce the application status and research progress of medical biological dressings in the field of wound healing, and reveal its development prospect to provide theoretical basis for the application of medical biological dressings in the progress of wound healing.
METHODS: The articles concerning medical biological dressings were retrieved in CNKI database and PubMed database from January 1998 to December 2008, using the key words of “medical dressing, biological material, chitosan, hydrogel, tissue engineering” in Chinese or “medical dressing, biological material, chitosan, hydrogel, tissue engineering” in English in the title and abstract. The content of articles related with wound healing and literatures recently published or published in authoritative magazines from the same field were selected. Totally 146 literatures were primarily selected (Chinese 107, English 39), according to inclusion criteria, 38 documents of which were involved for summarization.
RESULTS AND CONCLUSION: The medical dressings of the current clinical use and research were divided into natural material and synthetic macromolecule, inorganic material and composite according to the materials. Moreover, the problems of dressing products in the quality control were discussed, the further direction of dressing products was prospected, and a theoretical basis for research and development of dressing products were provided.