Abstract:

OBJECTIVE: To explore the role of chitosan for the prevention of postoperative intestinal adhesion.
METHODS: A computer-based online search of CNKI from 1989 to 2009 was conducted, three authors participated in the literature screening, data acquisition and quality evaluation. The intestinal ventilation time and the incidence of intestinal adhesion after surgery in chitosan-treated group and control group were compared in subjects met the inclusive criteria.
RESULTS: Totally fifteen studies were in accordance with the inclusive criteria. Results showed that, the intestinal ventilation time and the incidence of intestinal adhesion rate post-operation in chitosan-treated group was significantly lower than routine treatment group.
CONCLUSION: Chitosan can significantly reduce the incidence of intestinal adhesion rates and shorten intestinal ventilation time, chitosan can be well prevent intestine from adhesion after operation and promote gastrointestinal functional recovery.