Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (3): 495-498.doi: 10.3969/j.issn.1673-8225.2011.03.028

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Repair of bone exposed wounds using artificial dermis in 23 cases

Du Wei-li, Zhou Ye-ping, Tian Peng, Zhang Guo-an   

  1. Department of Burns, Beijing Jishuitan Hospital, Beijing   100035, China
  • Received:2010-09-02 Revised:2010-12-04 Online:2011-01-15 Published:2011-01-15
  • Contact: Zhou Ye-ping, Chief physician, Department of Burns, Beijing Jishuitan Hospital, Beijing 100035, China zhouyeping@yahoo.com
  • About author:Du Wei-li★, Master, Physician, Department of Burns, Beijing Jishuitan Hospital, Beijing 100035, China duweili@yahoo.cn

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Abstract:

BACKGROUND: In recent years, artificial dermis has been reported to repair bone exposed wound, but the treatment effect remains unclear.　
OBJECTIVE: To evaluate the therapeutic effect of artificial dermis in repairing bone exposure in 23 cases.
METHODS: A total of 23 patients with bone exposure were selected from the Department of Burns, Beijing Jishuitan Hospital, including 18 males and 5 females. Patients underwent debridement and artificial dermal transplantation, followed by split thickness autoskin transplantation. The survival of artificial dermis and split thickness autoskin was observed, as well as scar hyperplasia at the skin donor site. 
RESULTS AND CONCLUSION: The bone exposed wounds of 22 patients were completely recovered and scar formation were not observed at donor site after surviving of artificial dermis and split thickness autoskin, only skull exposure was partially covered in one femal patient. Artificial dermis has a good therapeutic effect in repairing bone exposure.

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