Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (3): 413-416.doi: 10.3969/j.issn.1673-8225.2011.03.008

Previous Articles     Next Articles

A comparison between titanium surgical mesh and bionic nano-bone in anterior cervical decompression and fusion

Yang Chao-lei, Wang Li-min, Liu Yi-lin, Tan Hong-yu, Wang Wei-dong   

  1. Department of Orthopedics, the First Affiliated Hospital of Zhengzhou University, Zhengzhou   450052, Henan Province, China
  • Received:2010-08-14 Revised:2010-10-15 Online:2011-01-15 Published:2011-01-15
  • Contact: Wang Li-min, Master, Professor, Master’s supervisor, Department of Orthopedics, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan Province, China gu2ke@yahoo.com.cn
  • About author:Yang Chao-lei★, Studying for master’s degree, Department of Orthopedics, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan Province, China chauly2003@163.com
  • Supported by:

    the National Science & Technology Pillar Program of China, No. 2007BAE13B00*

PDF

321

Abstract:

BACKGROUND: Nano-hydroxyapatite/polyamide as a new bone graft material is used in anterior cervical decompression and fusion, it not only reduces the complications after bone removal, and exhibits a stable graft fusion rate.
OBJECTIVE: To study clinical effect of titanium surgical mesh versus nano-hydroxyapatite and polyamide composite (n-HA/PA66) in anterior cervical decompression and fusion for treatment of cervical sondylotic myelopathy.
METHODS: A total of 48 cases of cervical spondylotic myelopathy were treated with anterior cervical subtotal corpectomy and fusion, titanium locking plates fixation, 26 with titanium surgical mesh, 22 with n-HA/PA66. The JOA grading system was done to evaluate neural functional restoration, and Cobb’s angle was measured to evaluate the change of cervical curvature. 
RESULTS AND CONCLUSION: All 48 patients were operated successfully and followed up for 6-14 months. The JOA grading scores were greatly improved in both groups at 3 months postoperation compared with before operation, without significant differences between two groups; at 3 and 6 months postoperation, the Cobb’s angle of all patients had significant differences compared with immediately after operation, without significant differences between two groups; 2 cases were evidenced subsidence of titanium surgical mesh and loss of vertebral height after three months of operation. N-HA/PA66 bionic bone as a graft of anterior cervical fusion has good fusion rate, and could effectively maintain the biological alignment and cervical intervertebral height. The long-term effects depend on further follow-up.

CLC Number: