Chinese Journal of Tissue Engineering Research ›› 2010, Vol. 14 ›› Issue (48): 9007-9010.doi: 10.3969/j.issn.1673-8225.2010.48.019

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Selection of the baseline in functional MRI study of acupuncture

Chen Shang-jie 1, 2, Peng Shu-ming3, Xu Ming-hui2, Zhang Jia-wei3, Shi Xue-min2   

  1. 1 Department of Rehabilitation, Baoan People’s Hospital of Shenzhen, Shenzhen  510170, Guangdong Province, China; 2 Tianjin University of Traditional Chinese Medicine, Tianjin  300193, China; 3 Guangzhou University of Traditional Chinese Medicine, Guangzhou  51006, Guangdong Province, China
  • Online:2010-11-26 Published:2010-11-26
  • About author:Chen Shang-jie☆, Doctor, Associate chief physician, Department of Rehabilitation, Baoan People’s Hospital of Shenzhen, Shenzhen 510170, Guangdong Province, China; Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China csjme@163.com
  • Supported by:

     the National Science Foundation for Post-doctoral Scientists of China, No. 20090460700*; the Science and Technology Program of Shenzhen, No. 200902159*

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Abstract:

BACKGROUND: Functional MRI (fMRI) is important to study acupoint specificity in recent year. Most of fMRI studies of acupuncture utilize the block design, and scanned after the needle is inserted. It is supposed that resting after needle into acupoint is pure rest and can be a baseline control. However, it is conflict with traditional Chinese acupuncture theory which thinks that acupuncture effect occurs after the needle into acupoint.
OBJECTIVE: To investigate how to choose baseline of acupuncture fMRI.
METHODS: Block design in Hui’s method was used. Acupuncture effect after needling into acupoint was analyzed to observe whether there was activation of brain function after needling into acupoint.
RESULTS AND CONCLUSION: It did not produce a certain function after tactile stimulus. But it produced a certain function after needling into acupoint. Rest phase after needling is not pure rest phase and is not a good baseline.

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