Chinese Journal of Tissue Engineering Research ›› 2010, Vol. 14 ›› Issue (48): 8998-9002.doi: 10.3969/j.issn.1673-8225.2010.48.017

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Dynamic MRI detection of cervical spondylotic myelopathy in the healthy and individuals with neck discomfort

Li Zhi-fei, Zhong Yuan-ming, Zhang Jia-li, Xu Jian-wen, Yang Guang, Wei Jia-ding, Wu Liang, Ma Xian-sheng, Tang Fu-bo   

  1. Department of Spinal Surgery, First Hospital of Guangxi Traditional Chinese Medical University, Nanning  530023, Guangxi Zhuang Autonomous Region, China
  • Online:2010-11-26 Published:2010-11-26
  • Contact: Zhong Yuan-ming, Master, Professor, Chief physician, Master’s supervisor, Department of Spinal Surgery, First Hospital of Guangxi Traditional Chinese Medical University, Nanning 530023, Guangxi Zhuang Autonomous Region, China zym196395@sina.com
  • About author:Li Zhi-fei★, Master, Attending physician, Department of Spinal Surgery, First Hospital of Guangxi Traditional Chinese Medical University, Nanning 530023, Guangxi Zhuang Autonomous Region, China zhifei815@yahoo.com.cn
  • Supported by:

    the Medical Treatment Key Program of Guangxi Zhuang Autonomous Region, No. 2008-20*; the Natural Science Foundation of Guangxi Zhuang Autonomous Region, No. 0848010*; the Science and Technology Development Program of Guangxi Zhuang Autonomous Region, No. 0993003A-14*

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Abstract:

BACKGROUND: MRI examination of cervical spondylotic myelopathy (CSM) is static plain scanning in a supine position with no movement or loading. Therefore, the spinal organic changes under loading and movement are omitted.
OBJECTIVE: To investigate the clinical significance of clinical manifestations in combination with cervical dynamic MRI in early diagnosis of CSM.
METHODS: A random sample of 10 normal population (normal group), 20 sub-health population with neck and shoulder discomfort (subhealth group), 20 patients with symptoms and signs of CSM, but not supported by conventional MRI (normal MRI CSM group), 20 CSM patients consistent with current diagnostic criteria (CSM group) were subjected to evaluation of JOA score, cervical spine lateral view, the neutral position of cervical spine MRI and dynamic MRI. They were followed up for at least 18 months, and index changes and transformations in four groups were observed. 
RESULTS AND CONCLUSION: CSM group were enrolled within six months treatment; Of 20 cases in normal MRI CSM group， 16 cases were treated in 16 months, and 4 in 1 year in the neutral position during MRI, which displayed no significant change; 12 patients with typical changes in 1 year in the neutral position after the cervical MRI underwent CSM surgical treatment, and the former treatment was better than the latter (P < 0.05); 4 cases in the subhealth group displayed CSM symptoms and signs, and the finding of their dynamic cervical MRI had signs of spinal canal narrowing of spinal cord compression, but the neutral position MRI revealed only one case of this change, who showed spinal cord compression on dynamic MRI at 12 months. In the follow-up of normal group, MRI in neutral position and dynamic MRI showed one case had spinal canal narrowing of spinal cord compression signs, but no symptoms were considered false-positive; the false positive rate was identical. Results showed that compared with MRI in neutral position, dynamic MRI can earlier and more realistic objective to display signs of spinal cord compression. In clinical symptoms and signs checks, MRI in neutral position in combination with dynamic MRI can early discover CSM.

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