Chinese Journal of Tissue Engineering Research ›› 2010, Vol. 14 ›› Issue (44): 8327-8330.doi: 10.3969/j.issn.1673-8225.2010.44.039

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Short and mid-term results of vacularized iliac crest graft for femoral head necrosis with sickle cell disease in juvenile patients

Wu Hao1, Liang Yuan2, Hernigou Philippe3   

  1. 1 Department of Orthopaedics, 2 Department of Radiology, People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning  530021, Guangxi Zhuang Autonomous Region, China; 3 Department of Orthopaedic and Traumatic Surgery, Henri Mondor Hospital, University of Paris XII, Créteil  94010, France
  • Online:2010-10-29 Published:2010-10-29
  • About author:Wu Hao, Chief physician, Department of Orthopaedics, People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, Guangxi Zhuang Autonomous Region, China wuhaorthop@yahoo.com.cn

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Abstract:

BACKGROUND: Sickle cell disease is the main reason for the ischemic necrosis of the femoral head in African juvenile patients. There are more reports concerning vascularized iliac graft for femoral head necrosis. It is also effective for the treatment of femoral head necrosis with sickle cell disease.
OBJECTIVE: To investigate the short and mid-term results of the vacularized iliac graft for ischemic necrosis of the femoral head in young patients with sickle cell disease.
METHODS: Totally 12 patients suffered from ischemic necrosis of the femoral head with sickle cell disease were treated with vascularized iliac graft in Maradi Province Hospital of Niger. The patients were followed up 24-30 months after operation (mean 27 months). The effects were evaluated on the basis of the Harris hip score and radiological examination.
RESULTS AND CONCLUSION: The clinical results were satisfactory though the radiological was not satisfied. The mean Harris hip score increased from 75 points to 90 points. Pain relief and hip function improvement were achieved in all patients. No patients needed revision during short and mid-term follow up. This method is recommendation for treatment of ischemic necrosis of the femoral head in the Ficat Stages Ⅲ-Ⅳ in juvenile patients with sickle cell disease for pain relief and restoration of hip joint function.

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