Chinese Journal of Tissue Engineering Research ›› 2010, Vol. 14 ›› Issue (42): 7915-7918.doi: 10.3969/j.issn.1673-8225.2010.42.030

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Surface modification of artificial ligaments and their application in knee cruciate ligament reconstruction

Zhao Xu-hui1, Wang Fang2    

  1. 1 Department of Physical Education, 2 Library of Shijiazhuang College, Shijiazhuang   050035, Hebei Province, China
  • Online:2010-10-15 Published:2010-10-15
  • About author:Zhao Xu-hui★, Master, Lecturer, Department of Physical Education, Shijiazhuang College, Shijiazhuang 050035, Hebei Province, China Zhaoxuhui76@126.com

Abstract:

OBJECTIVE: To review the surface modification techniques of artificial ligaments and its efficacy in reconstruction of knee joint cruciate ligament.
METHODS: A computer research was performed in Wanfang database (http://www.wanfangdata.com.cn/) from January 2000 to August 2010 to retrieve articles about the surface modification techniques of artificial ligaments and its application in reconstruction of knee joint cruciate ligament, using key words of “artificial ligament, surface modification, cruciate ligament” in Chinese. Repeated study, general review or Meta analysis were excluded, 33 literatures were screened into the evaluation.
RESULTS: The surface modification of biomaterials is a complicated system, needs both material science and biological science requirements, achieving the desired surface modification should design he surface topology structure-specific recognition- hydrophilic/hydrophobic balance-protein adsorption. Current surface modification techniques are mainly fixed peptide, fixed proteins, laser surface modification, radiation grafting, ion implantation, grafting modification. Through biological materials surface modification, cell adhesion is enhanced, cell proliferation is also promoted.
CONCLUSION: The artificial ligament surface modification technology may achieve remarkable results to improve the biocompatibility of artificial materials, with a good application prospect.

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