Chinese Journal of Tissue Engineering Research ›› 2010, Vol. 14 ›› Issue (39): 7398-7401.doi: 10.3969/j.issn.1673-8225.2010.39.044

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Total hip arthroplasty for avascular necrosis of the femoral head in 6 patients with systemic lupus erythematosus

Zhang Zi-ji1, Yu Shi-ming2, Kang Yan1, Lei Zi-xiong2, He Ai-shan1, Fu Ming1, Yang Zhong-han1, Liao Wei-ming 1,2, Sheng Pu-yi 1,2   

  1. 1 Department of Orthopedics, First Affiliated Hospital, Sun Yat-sen University, Guangzhou  510080, Guangdong Province, China; 2 Huangpu Joint Surgery Center, First Affiliated Hospital of Sun Yat-sen University, Guangzhou  510700, Guangdong Province, China
  • Online:2010-09-24 Published:2010-09-24
  • Contact: Sheng Pu-yi, Associate professor, Associate chief physician, Department of Orthopedics, First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China shengpuyi@hotmail.com
  • About author:Zhang Zi-ji☆, Studying for doctorate, Department of Orthopedics, First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China zhangziji1984@sina.com
  • Supported by:

    the International Cooperation Program of Guangdong Provincial Science and Technology Commission, No. 2006B50107004*; Guangdong Provincial Science and Technology Commission Program, No. 2007B010600048*

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Abstract:

BACKGROUND: Total hip arthroplasty (THA) is the major method for treating hip joint disease at terminal stage with a precise effect. However, avascular necrosis of the femoral head (AVNFH) patients with systemic lupus erythematosus (SLE) are often complicated with severe osteoporosis or other disease. The effect of THA for these patients remains unclear.
OBJECTIVE: To explore the clinical outcome of THA for AVNFH in patients with SLE.
METHODS: A retrospective study was conducted for SLE patients with AVNFH from June 1998 to June 2008. A total of 6 patients were followed up (6 hips), including 1 male and 5 females, aged 46 years old (range 28 to 67 years), 5 bio-typed and 1 bone-cemented type. The treatment effects were evaluated using Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Medical Outcome Survey Short Form 36 (SF-36) and Harris hip score.
RESULTS AND CONCLUSION: The mean operation time was 141 minutes (85 to 210 minutes), bleeding 522 mL (180 to 1 500 mL). An average follow-up of 3.5 years (range from 1 to 10 years) were assessed. One patient died of hypertension 1.5 years after surgery, and 1 case developed urinary system infection early following postoperation. No infection, loosening, dislocation or deep venous thrombosis was observed. The average Harris Hip score, WOMAC scores and SF-36 were significantly improved compared with preoperative scores (P < 0.05). THA significantly improves quality of life of patients with SLE and AVNFH with good mid-term results after THA.

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