Chinese Journal of Tissue Engineering Research ›› 2010, Vol. 14 ›› Issue (39): 7327-7330.doi: 10.3969/j.issn.1673-8225.2010.39.026

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3D hemodynamic numerical simulation of intracranial aneurysms before and after embolism treatment based on image data

Yu Hong-yu1, Li Hai-yun1, Zhang Ying2, Yang Xin-jian2　   

  1. 1 Capital Medical University School of Biomedical Engineering, Beijing  100069, China; 2 Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, Beijing  100050, China　
  • Online:2010-09-24 Published:2010-09-24
  • Contact: Li Hai-yun, Doctor, Professor, Doctoral supervisor, Capital Medical University School of Biomedical Engineering, Beijing 100069, China
  • About author:Yu Hong-yu☆, Studying for doctorate, Lecturer, Capital Medical University School of Biomedical Engineering, Beijing 100069, China ruby_y@tom.com
  • Supported by:

     the National Natural Science Foundation of China, No. 30772234*

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Abstract:

BACKGROUND: Intracranial aneurysms are pathological dilatations of the arterial wall. Hemodynamic factors play an important role in the formation, growth and rupture of intracranial aneurysms. Therefore, the computational numerical simulation technique based on computational fluid hydrodynamics has been used widely in this field.
OBJECTIVE: To explore the relationship between the change of the wall shear stress before and after treatment and recrudescence of intracranial aneurysms.
METHODS: 3-D models of intracranial aneurysms were created based on patient-specific anatomical images and performed hemodynamic numerical simulation of the models of two patients before and after embolism treatment.
RESULTS AND CONCLUSION: For the recrudescent case, the wall shear stress at the neck of the aneurysm was considerably greater than before treatment. While, for the unrecrudescent case, the wall shear stress at the neck of the aneurysm was lower than before treatment. If the wall shear stress at the neck of the aneurysm is lower than before treatment, the risk of recrudescence is low; otherwise, the risk of recrudescence is high.

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