Chinese Journal of Tissue Engineering Research ›› 2010, Vol. 14 ›› Issue (26): 4933-4936.doi: 10.3969/j.issn.1673-8225.2010.26.045

Previous Articles     Next Articles

Controlled hypotension combined with autotransfusion in patients with idiopathic scoliosis

Yin Xiang, Wang Ai-min, Sun Hong-zhen, Du Quan-yin, Wang Zi-ming, Wang Yu   

  1. Department of Orthopedics, Research Institute of Surgery, Third Affiliated Hospital, Third Military Medical University of Chinese PLA, Chongqing  400042, China
  • Online:2010-06-25 Published:2010-06-25
  • About author:Yin Xiang, Master, Physician, Department of Orthopedics, Research Institute of Surgery, Third Affiliated Hospital, Third Military Medical University of Chinese PLA, Chongqing 400042, China yinx2000sw@ tom.com

Abstract:

BACKGROUND: Idiopathic scoliosis is a common spinal deformity in teenagers, which is managed mainly by orthomorphia. However, due to great trauma, long operative duration and large blood loss, a great amount of blood transfusion is needed during the surgery. Allogeneic blood transfusion should be reduced in order to release blood insufficient, decline blood transfusion expense, as well as avoid transfusion diseases.

OBJECTIVE: To investigate the value of controlled hypotension combined with autotransfusion in idiopathic scoliosis orthomorphia.

METHODS: Intraoperative controlled hypotension was performed during posterior orthomorphia surgery on all the 46 cases of idiopathic scoliosis, 17 cases in which were served as the control group, who underwent allogeneic blood transfusion without autotransfusion, while the other 29 cases were served as the experimental group, who underwent autotransfusion that including reinfusion of preoperative deposited autologous blood and intra-operative salvaged autologous blood. The blood loss volume and transfusion status in two groups were observed.

RESULTS AND CONCLUSION: Blood loss volume in the control group was 400-1 000 (867±161) mL, and that in the experimental group was 350-1400 (842±376) mL, There was no marked difference between the two groups (P > 0.05). The volume of allogeneic blood transfusion in the control group was 500-1 800 (845±332) mL, which was greater than that in the experimental group [0-1 300(423±237) mL] (P < 0.01). The results suggested that controlled hypotension reduces intraoperative bleeding, and postoperative autotransfusion minimizes the need of allogeneic blood transfusion.

CLC Number: