Chinese Journal of Tissue Engineering Research

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Research and application features of stem cells in dentistry

Sha Ri-na, Wu Yan   

  1. Department of Histology and Embryology, Inner Mongolia Medical College, Hohhot 010059, Inner Mongolia Autonomous Region, China
  • Online:2010-04-02 Published:2010-04-02
  • Contact: Wu Yan, Professor, Doctor, Master’s supervisor, Department of Histology and Embryology, Inner Mongolia Medical College, Hohhot 010059, Inner Mongolia Autonomous Region, China yanw007@sina.com
  • About author:Sha Ri-na★, Studying for master’s degree, Physician, Department of Histology and Embryology, Inner Mongolia Medical College, Hohhot 010059, Inner Mongolia Autonomous Region, China sharina103@163.com

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Abstract:

BACKGROUND: The dental pulp stem cells, marrow mesenchymal stem cells and periodontal ligament stem cells belong to the adult stem cells from oral cavity, which own two features of the adult stem cells: the ability of renewing themselves strongly and the potential of splitting. Through the continuous study of many kinds of stem cells from oral cavity, it is very helpful for human to show the process of making the firm organizations of tooth and the inducing mechanism, in order to direct the related clinical work and the prevention work.
OBJECTIVE: To summarize features and application perspective of various adult stem cells from oral cavity in the clinic.
METHODS: The first author retrieved PubMed database (http://www.ncbi.nlm.nih.gov/PubMed) and China National Knowledge Infrastructure (http://www.cnki.net) for relevant literatures published from January 1999 to December 2009. The key words were “stem cell, dentistry”. A total of 80 literatures were screened, and studies on basic research and clinical application of stem cells in stomatology medical field were included. Old and duplicated studies were excluded and finally 19 literatures were included.
RESULTS AND CONCLUSION: With development of study, adult stem cells in oral cavity will be gradually found to establish integrated stem cell database, which can provide cell source for tissue engineering study in the oral cavity.

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