Abstract:

BACKGROUND: High pulse pressure is the signal of arteriosclerosis or cardiovascular diseases for both hypertension and normal blood pressure population.
OBJECTIVE: The pulse pressure and related factors of healthy adults in Sichuan province were analyzed to explore the method for preventing excessive pulse pressure and improving the quality of life.
METHODS: Hierarchical, cluster sampling were performed in 1 989 healthy adults. The physical examination, blood glucose, renal function and blood fat were detected, and the relation of pulse pressure and its related factors were analyzed.
RESULTS AND CONCLUSION: Pulse pressure increased following the age, especially showed a linear increasing in those who more than 50-year-old. The increased pulse pressure leaded to larger fasting plasma glucose, uric acid, blood urea nitrogen, total cholesterol, triacylglycerol, systolic pressure and diastolic pressure, in addition, the age, body mass index, waist-to-hip ratio, triacylglycerol and pulse pressure showed a linear relationship. But physical exercise was negative correlated to pulse pressure. With pulse pressure increasing, the renal function and regulating capacity of blood glucose was decreased. The results suggested that mid-aged population should take reasonable diet and more physical exercise to prevent central obesity and excessive pulse pressure, reduce the risk of renal dysfunction and the incidence of cardiovascular disease.