Nano-hydroxyapatite artificial bone for collapsed fractures of the tibial plateau

doi:10.3969/j.issn.2095-4344.2013.51.013

Abstract

Abstract:

BACKGROUND: Nano-hydroxyapatite helps to improve the mechanical properties of bone implants.
OBJECTIVE: To study the clinical effect of nano-hydroxyapatite artificial bone on collapsed fracture of the tibial plateau.
METHODS: Fourteen cases of collapsed fracture of the tibial plateau combined with bone defects from March 2010 to September 2012 were analyzed retrospectively. The bone defect range was from 1.5 cm×1.0 cm to 3.1 cm×4.5 cm. All patients were treated with nano-hydroxyapatite artificial bone at an implant amount of 5-14 g. Clinical and X-ray observations were applied at 1 week, 1 month and 3 months postoperatively. Hospital for Special Surgery scores were employed for recovery of knee function.
RESULTS AND CONCLUSION: The patients were followed up for 12-27 months. Except for one case of a small amount of wound exudates, no general side effects occurred in 13 cases. X-ray photo showed an integrity interface between nano-hydroxyapatite artificial bone and host bone at 3 months after treatment. Primary healing was obtained in all cases without any complications. Hospital for Special Surgery score was increased to (88.7±4.3) points at 1 year later. These findings indicate that the nano-hydroxyapatite artificial bone has a good biocompatibility and biomechanics, and it may be an ideal artificial bone for repairing collapsed fractures of the tibial plateau.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

全文链接：

Key words: biocompatible materials, nanoparticles, hydroxyapatites, fractures, bone

CLC Number:

R318

Wang Da-ping, Xiong Jian-yi, Zhu Wei-min, Huang Jiang-hong, Duan Li, Chen Jie-lin,Zhang Ju-feng. Nano-hydroxyapatite artificial bone for collapsed fractures of the tibial plateau[J]. Chinese Journal of Tissue Engineering Research, 2013, 17(51): 8863-8868.

Figures/Tables 2

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