Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (4): 653-656.doi: 10.3969/j.issn.1673-8225.2011.04.019

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Three-dimensional visualization of human cutaneous microvasculature 

Guo Zhi-yong1, Ding Hong-mei2, Yin Zhi-xun1, Dong Wei-qiang1, Bai Bo1, Peng Tian-hong3   

  1. 1Department of Orthopaedic Surgery, First Affiliated Hospital of Guangzhou Medical College, Guangzhou  510120, Guangdong Province, China
    2Department of Anatomy, Guangzhou Medical College, Guangzhou  510515, Guangdong Province, China
    3Department of Anatomy, University of South China, Hengyang  421200, Hunan Province, China
  • Received:2010-07-23 Revised:2010-08-28 Online:2011-01-22 Published:2011-01-22
  • Contact: Yin Zhi-xun, Doctor, Associate chief physician, Department of Orthopaedic Surgery, First Affiliated Hospital of Guangzhou Medical College, Guangzhou 510120, Guangdong Province, China yzhixun@163.com
  • About author:Guo Zhi-yong, Attending physician, Department of Orthopaedic Surgery, First Affiliated Hospital of Guangzhou Medical College, Guangzhou 510120, Guangdong Province, China
  • Supported by:

    the Medical Science and Technology Research Foundation of Guangdong Province, No. WSTJJ20081125432928196601020416*

Abstract:

BACKGROUND: Angiotomy methods such as dissection, ink injection and angiographs techniques have been used to identify vessel location. However, these techniques rarely provide a steric architecture of the cutaneous angiosome.
OBJECTIVE: To establish three-dimensional (3D) architecture of the cutaneous angiosome for assessing and designing perforator flaps.
METHODS: Two fresh cadavers were injected with carboxymethyl cellulose/lead oxide and subjected to CT scanning before and after the injection to obtain data of the cutaneous and subcutaneous tissue derived from one injected cadaver. Three-dimensional reconstruction and perforator flaps design were performed using Mimics13.1 software.
RESULTS AND CONCLUSION: Three-dimensional digital models of the bone, blood vessels, skin were obtained. The flap with total perforator of external femoral circumflex artery and the flap with main perforator of posterior humeral circumflex artery were developed. The 3D microvascular architecture model can clearly display the spatial location, distribution range and anastomose relationship of the cutaneous perforators, the caliber, length, position of particular source artery in the exact spatial location. As a result, it visualized the general area and expandable direction of a respective flap. This technique facilitates perforator flaps design and blood supply evaluation.

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