Chinese Journal of Tissue Engineering Research ›› 2010, Vol. 14 ›› Issue (52): 9877-9880.doi: 10.3969/j.issn.1673-8225.2010.52.047

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Central arterial augmentation index in Uygur health adults from Hetian, Xinjiang
Detection by Sphygmocor pulse wave analysis system

Liang Xiao-hui1, Xu Xin-juan1, Ma Yan-ping1, Sun Li-hua1, Ma Yi-tong2, Huang Ding2, Yang Yi-ning2   

  1. 1 Department of Hypertension, 2 Department of Coronary Heart Disease, First Affiliated Hospital, Xinjiang Medical University, Urumqi  830054, Xinjiang Uygur Autonomous Region, China
  • Online:2010-12-24 Published:2010-12-24
  • Contact: Xu Xin-juan, Chief physician, Professor, Doctoral supervisor, Department of Hypertension, First Affiliated Hospital, Xinjiang Medical University, Urumqi 830054, Xinjiang Uygur Autonomous Region, China zcxu2002@medmail.com.cn
  • About author:Liang Xiao-hui☆, Studying for doctoral degree, Attending physician, Department of Hypertension, First Affiliated Hospital, Xinjiang Medical University, Urumqi 830054, Xinjiang Uygur Autonomous Region, China lxhforum@163.com
  • Supported by:

    the National Natural Science Foundation of China, No. 30860296*

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Abstract:

BACKGROUND: Arterial stiffness is an independent risk factor for cardiovascular disease. Augmentation index (AIx) is an important marker which reflects the systemic arterial stiffness.
OBJECTIVE: To investigate AIx and the affecting factors in Xinjiang Uygur health adults.
METHODS: A total of 559 healthy adults (251 males and 308 females) with a mean age of (44.95±11.87) years were selected from Hetian, Xinjiang Uygur Autonomous Region. The following indexes of all subjects were measured, including questionnaire, physical examination, blood biochemistry and C-reactive protein (CRP). Central systolic blood pressure (cSBP) and central AIx were measured by Sphygmocor. Pearson correlation and partial correlation analysis were used for two-group analysis of correlation, and multiple regression analysis was used to analyze influential factors for AIx.
RESULTS AND CONCULUSION: AIx was greater in female than in male and was positively related to age in both sexes (male: r=0.548, female: r =0.405, P < 0.05), as well as adjusted other influential factors (male: r=0.182, female: r =0.234, P < 0.05). Multiple regression analysis showed that cSBP, systolic blood pressure (SBP), sex, age and CRP were main factors which affected AIx in Uygur healthy adults. cSBP, SBP, age, body mass and CRP were main factors which affected AIx in the male, while cSBP, SBP, age, height and CRP were main factors which affected AIx in the female. Results revealed that AIx was greater in female than in male which was positively related to age in both sexes. Age, cSBP, SBP and CRP were main factors that affected AIx in Xinjiang Uygur healthy adults.

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