Abstract:

BACKGROUND: To data, there is no consistent conclusion on the effect of anterior cervical discectomy and fusion (ACDF) and artificial disc replacement in the treatment of cervical spondylosis.
OBJECTIVE: To compare the effect of anterior cervical discectomy and artificial disc replacement in the treatment of cervical spondylosis.
METHODS: 106 patients with cervical spondylosis were selected from Department of Orthopedics, the First Affiliated Hospital of Zhengzhou University to perform the retrospective analysis. Nineteen patients received Bryan artificial disc replacement (replacement group), 87 patients received single-level ACDF (ACDF group).
RESULTS AND CONCLUSION: All the patients were followed-up for 36-48 months. ①The neurological function of two groups was significantly restored during follow-up, and there was no significant difference of visual analogue scores and JOA scores between two groups during final follow-up (P > 0.05). ②All patients of the ACDF group achieved bone fusion at 6 months after operation without internal fixation loosening, dislocation or breakage. No complications such as prosthesis migration or loosening occurred in replacement group. As for the range of motion of cervical vertebrae and the replacement segment of cervical vertebrae, there was no statistical difference before and after operation (P > 0.05). No serious complications occurred. Single-level artificial disc replacement has fewer complications in the early stage, and the Bryan artificial disc replacement can achieve the satisfactory clinical outcome and preserve the range of motion of cervical vertebrae and the replacement segment of cervical vertebrae.