Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (32): 6058-6062.doi: 10.3969/j.issn.2095-4344.2012.32.032

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Research progress of cancer stem cells in urologic cancers

Liu Yu, Gou Xin   

  1. Department of Urology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China
  • Received:2011-12-03 Revised:2011-12-14 Online:2012-08-05 Published:2012-08-05
  • Contact: Gou Xin, Professor, Chief physician, Department of Urology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China
  • About author:Liu Yu★, Studying for master’s degree, Department of Urology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China tommyliuyu@gmail.com

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Abstract:

BACKGROUND: Although the research about the cancer stem cells from urologic cancers is late, it also makes some achievements.
OBJECTIVE: To review the research progress of urologic cancer stem cells in recent years.
METHODS: Articles related to the research progress of urologic cancer stem cells in PubMed database from January 1997 to August 2011 were retrieved by the computer with the key words “cancer stem cell, urologic cancer”. A total of 289 articles were obtained from the database. The repetitive articles and non-compliant articles were excluded, and finally 30 articles were included for further analysis.
RESULTS AND CONCLUSION: As the in-depth study of cancer stem cells, more and more cancer stem cells have been identified and isolated from kinds of tumors, and cancer stem cells in urologic cancers have acquired some advancement. Their biological characteristics, self-regulatory mechanisms and micro-environment are further understood by researches, and cancer stem cells targeted therapy will become a new way for curing urologic cancers in the future.

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