Safety and effectiveness of autologous blood transfusion after total hip arthroplasty

Chinese Journal of Tissue Engineering Research ›› 2016, Vol. 20 ›› Issue (4): 465-469.

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Safety and effectiveness of autologous blood transfusion after total hip arthroplasty

Zhao Ji-tong, Jiang Zhong, Chen Jun-feng, Cao Xiao-dong, Luo Yuan, Shen Wei-zhong

the First People’s Hospital of Taicang, Suzhou University, Taicang 215400, Jiangsu Province, China

Received:2015-11-20 Online:2016-01-22 Published:2016-01-22
Contact: Jiang Zhong, Associate chief physician, the First People’s Hospital of Taicang, Suzhou University, Taicang 215400, Jiangsu Province, China
About author:Zhao Ji-tong, Master, Physician, the First People’s Hospital of Taicang, Suzhou University, Taicang 215400, Jiangsu Province, China
Supported by:
the Project of Suzhou Municipal Science and Technology Bureau, No. SYD2014034

Abstract

Abstract:

BACKGROUND: Autologous blood transfusion device has been widely used in the clinic, reduces allogeneic blood transfusion, and avoids the occurrence of blood transfusion complications, and effectively improves the patient’s blood safety, but the application of autologous blood transfusion after total hip arthroplasty has been seldom reported.
OBJECTIVE: To discuss the safety and effectiveness of autologous blood transfusion after total hip arthroplasty.
METHODS: 200 patients were treated by primary unilateral total hip arthroplasty from March 2013 to March 2015. They were randomly divided into two groups. 127 patients in the autologous blood transfusion group received
autologous blood transfusion by a drainage tube. 73 patients in the negative pressure drainage ball group received a negative pressure drainage tube. The standard for allogeneic blood transfusion after replacement was hemoglobin < 80 g/L. The changes in hemoglobin were compared before and 1 and 7 days after replacement between the two groups. Total drainage volume and allogeneic blood transfusion were compared within 6 hours after replacement between the two groups.
RESULTS AND CONCLUSION: There were no statistical differences in hemoglobin levels at 7 days before and after replacement, in drainage volume within 6 hours and the total drainage volume between the two groups (P > 0.05). Hemoglobin levels were significantly higher in the autologous blood transfusion group than in the negative pressure drainage ball group at 1 day after replacement (P < 0.05). In the autologous blood transfusion group, autologous blood transfusion volume was averagely 324.2 mL. Allogeneic blood transfusion volume was averagely 146.7 mL in 31 patients. No reaction was found after autologous blood transfusion. In the negative pressure drainage ball group, 49 patients received allogeneic blood transfusion (averagely 261 mL). The volume and proportion of allogeneic blood transfusion were significantly lower in the autologous blood transfusion group than in the negative pressure drainage ball group (P < 0.05). Among patients receiving allogeneic blood transfusion, seven patients affected pyrogenetic reaction during blood transfusion. These findings suggested that autologous blood transfusion is simple and effective, can effectively reduce the volume and reaction of allogeneic blood transfusion after total hip arthroplasty and avoid blood-borne diseases, with good prospects.

中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程

Zhao Ji-tong, Jiang Zhong, Chen Jun-feng, Cao Xiao-dong, Luo Yuan, Shen Wei-zhong. Safety and effectiveness of autologous blood transfusion after total hip arthroplasty[J]. Chinese Journal of Tissue Engineering Research, 2016, 20(4): 465-469.

Figures/Tables 5

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Safety and effectiveness of autologous blood transfusion after total hip arthroplasty

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