Chinese Journal of Tissue Engineering Research ›› 2015, Vol. 19 ›› Issue (46): 7539-7544.doi: 10.3969/j.issn.2095-4344.2015.46.029

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Ilizarov bone transport for repair of diabetic foot: a functional and imaging evaluation

Xian Cheng, Zhao Jin-min, Su Wei, Lao Shan, Yang Xin, Hua Qi-kai   

  1. Hua Qi-kai, M.D., Master’s supervisor, Associate chief physician, Department of Bone and Joint Surgery, First Affiliated Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China
  • Received:2015-10-08 Online:2015-11-12 Published:2015-11-12
  • Contact: Hua Qi-kai, M.D., Master’s supervisor, Associate chief physician, Department of Bone and Joint Surgery, First Affiliated Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China
  • About author:Xian Cheng, Studying for master’s degree, Department of Bone and Joint Surgery, First Affiliated Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China
  • Supported by:

    the Natural Science Foundation of Guangxi Zhuang Autonomous Region, No. 2014GXNSFAA118229

Abstract:

BACKGROUND: Previous therapies for diabetic foot are not ideal with large cost, and moreover, amputation is often required.

OBJECTIVE: To perform the Ilizarov bone transport in the treatment of patients with diabetic foot (Wanger grades 3-4), and to observe the limb salvage conditions.
METHODS: Eighteen patients with diabetic foot, Wanger grades 3-4, admitted in the Department of Bone and Joint Surgery, First Affiliated Hospital of Guangxi Medical University from December 2013 to June 2015 were enrolled in this trial. All of patients were subjected to Ilizarov bone transport.
RESULTS AND CONCLUSION: All the 18 patients were followed up for 3 to 20 months, and presented with ulcer healing. Scores on ankle-brachial index and 10-g nylon line test were both increased significantly in the patients after treatment, but the visual analog scale scores were reduced. These findings indicate that the Ilizarov bone transport is an effective method for treating ulcer of diabetic foot at Wanger grades 3-4. 
中国组织工程研究杂志出版内容重点:组织构建;骨细胞;软骨细胞;细胞培养;成纤维细胞;血管内皮细胞;骨质疏松组织工程

Key words: Diabetic Foot, Ulcer, External Fixators, Tissue Engineering