Preparation and characterization of polymethylmethacrylate-based magnetic bone cements containing micron carbonyl iron powder

doi:10.3969/j.issn.2095-4344.2013.47.003

Abstract

Abstract:

BACKGROUND: Magnetic bone cements have been used to treat bone metastasis in Japan, which are made by adding Fe3O4 nanoparticles to bone cements. Magnetic bone cements containing micron carbonyl iron powder have not been reported.
OBJECTIVE: To prepare polymethylmethacrylate-based cements containing carbonyl iron powder, and to test the magnetic characterizations and the heat-generating abilities of all samples according to ISO 5833 standard in vitro.
METHODS: The carbonyl iron powder was mixed with polymethylmethacrylate-based bone cement power to prepare magnetic bone cements containing 0%, 20%, 30%, 40%, and 50% carbonyl iron powder, respectively. The setting time, polymerization temperature, compressive strength, magnetic property and in vitro heat-generating ability were tested.
RESULTS AND CONCLUSION: The setting time and polymerization temperature were increased with the increased content of carbonyl iron powder. The highest polymerization temperature of each sample was 65-70 ℃. The increased content of carbonyl iron power could not change the highest polymerization temperature but delay its appearance. The compressive strength of each sample was higher than 60 MPa, and moreover, the compressive strength of the pure polymethylmethacrylate-based bone cement was higher than 60 MPa, which met the ISO 5833 standard. The saturation magnetic intensity was increased with the increasing of carbonyl iron power content. The heat-generating ability of magnetic bone cements had a positive correlation with the magnetic field strength and the content of carbonyl iron powder.

Key words: biocompatible materials, polymethacrylic acids, magnetic field therapy, iron carbonyl compounds

CLC Number:

R318

Hu Yan-wen, Wang Xiao-wen, Tang Zheng-hai, Wei Lang-bin, Pang Rui, Tang Jin-tian. Preparation and characterization of polymethylmethacrylate-based magnetic bone cements containing micron carbonyl iron powder[J]. Chinese Journal of Tissue Engineering Research, 2013, 17(47): 8155-8161.

Figures/Tables 4

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