Application and prospect of adipose-derived stem cells in wound inflammation

doi:10.3969/j.issn.2095-4344.1774

Abstract

Abstract:

BACKGROUND: Since human embryonic stem cells were successfully obtained in 1998, clinicians have been trying to use stem cells in wound healing. Importantly, stem cells can regulate wound inflammation.
OBJECTIVE: To investigate the application and prospect of adipose-derived stem cells in wound inflammation.
METHODS: The first author searched CNKI and PubMed databases (from 1999 to October 2018) with the retrieval words of “adipose-derived stem cells, wound, inflammation” in Chinese and English, respectively. Literatures regarding adipose-derived stem cells, wound and inflammation were selected. The articles published lately or authoritatively in the same field were preferred.
RESULTS AND CONCLUSION: Wound healing is a complex and orderly process, and closely related to wound inflammation. With the development of regenerative medicine, the application of stem cells brings a new approach to wound healing. Adipose-derived stem cells have a promising prospect as characterized by the strong abilities of proliferation and multidirectional differentiation, easy to obtain, and abundant sources. To date, adipose-derived stem cells are still one of the most popular candidates for regulating wound inflammation and promoting wound healing.

Key words: stem cells, adipose-derived stem cells, mesenchymal stem cells, wounds, inflammation, wound healing, wound repair, review

CLC Number:

Zhang Liming, Cai Jieyun, Pan Fuqiang, Wang Jing. Application and prospect of adipose-derived stem cells in wound inflammation[J]. Chinese Journal of Tissue Engineering Research, 2019, 23(25): 4089-4093.

Figures/Tables 1

References

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