Significance of routine magnetic resonance imaging examination in evaluating osteoporosis of the lumbar spine

doi:10.3969/j.issn.2095-4344.1014

Abstract

Abstract:

BACKGROUND: MRI of lumbar spine has been more and more extensively applied in patients with low back pain. The conventional MRI signal of lumbar spine is high in older females, which may be related to osteoporosis.

OBJECTIVE: To investigate the significance of conventional signal changes on MRI of lumbar spine in evaluating lumbar osteoporosis.

METHODS: One hundred and ninety-four cases were collected whose bone mineral density was determined by dual-energy X-ray absorptiometry and MRI in the L₁-L₄ within 1 month, including 50 males and 144 females. Dual-energy X-ray absorptiometry-bone mineral density value and MRI signal of lumbar vertebrae in the sagittal plane MRI-T₁WI, T₂WI and FS-T₂WI and signal difference between T₂WI and FS-T₂WI were analyzed. With 1 g/cm² as the dividing line, the dual-energy X-ray absorptiometry- bone mineral density value and the value of MRI signal of vertebral bodies were compared.

RESULTS AND CONCLUSION: (1) Bone mineral density of female subjects in all four vertebral bodies were significantly lower than that of males, in addition to P=0.003 in L₄, the rest P < 0.001. (2) The FS-T₂WI was not significantly different between males and females (P > 0.05). In females, the signals of MR-T₁WI, T₂WI and signal difference between MR-T₂WI and FS-T₂WI in the sagittal plane of lumbar vertebrae were significantly higher than those in males (P ≤ 0.001). (3) Among different age groups, dual-energy X-ray absorptiometry-bone mineral density and signals of MRI-T₁WI, T₂WI and signal difference between MRI-T₂WI and FS-T₂WI were significantly different. (4) In addition to the L₄, dual-energy X-ray absorptiometry-bone mineral density of patients under 60 years old was significantly higher than that of patients over 60 years old (P < 0.05), and decreased with age increasing. (5) While the signals of MRI-T₁WI, T₂WI and signal difference between MR-T₂WI and FS-T₂WI of patients under 60 years old were significantly lower than that of patients over 60 years old (P < 0.05), and increased with age increased. (6) There were no significant differences in the signal of MRI-FS-T₂WI of all age groups. (7) The age and signals of MRI-T₁WI, T₂WI and signal difference between MRI-T₂WI and FS-T₂WI of subjects of dual-energy X-ray absorptiometry-bone mineral density ≥ 1 g/cm² were significantly lower than that < 1 g/cm² (P < 0.001), while vertebral signals were not significantly different in FS-T₂WI (P > 0.05). (8) These results indicate that dual-energy X-ray absorptiometry can quantitatively determine the bone mineral density. MRI can reflect the content of bone fat and water by changes of signal by multi-sequences. It has important significance to judge the content of bone minerals and bone matrix indirectly.

中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程

Key words: Osteoporosis, Bone Density, Minerals, Absorptiometry, Photon, Magnetic Resonance Imaging, Tissue Engineering

CLC Number:

R445.2

Weng Zijing, Huang Xuejing, Yu Jianli, Zhang Minguang. Significance of routine magnetic resonance imaging examination in evaluating osteoporosis of the lumbar spine [J]. Chinese Journal of Tissue Engineering Research, 2018, 22(35): 5667-5673.

Figures/Tables 4

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