Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (47): 8927-8930.doi: 10.3969/j.issn.1673-8225.2011.47.047

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Application of acellular dermal matrix in treatment of unilateral vocal cord paralysis

Liu Rong-rong, Li Hong-tao, Zhang Min, Xiao Ya   

  1. Department of Otolaryngology, Institute of Battle Surgery, Daping Hospital, the Third Military Medical University of Chinese PLA, Chongqing  400042, China
  • Received:2011-05-02 Revised:2011-07-04 Online:2011-11-19 Published:2011-11-19
  • About author:Liu Rong-rong☆, Doctor, Attending physician, Department of Otolaryngology, Institute of Battle Surgery, Daping Hospital, the Third Military Medical University of Chinese PLA, Chongqing 400042, China Rongrongliu123@126.com

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Abstract:

BACKGROUND: Acellular dermal matrix (ADM), as a new material which has good biologic and structural compatibility, is generally applied to tissue repair and padding in operations on head and neck.
OBJECTIVE: To investigate the short- and long-term effect of ADM on vocal cord paralysis.
METHODS: Totally 20 patients with unilateral complete recurrent laryngeal nerve paralysis were selected (the affected vocal cord was fixed at the side-centric position). The curative effect and risk of the operation of padding ADM under the affected vocal cord were observed by windowing on the lamina cartilaginis thyroidea under local anesthesia to improve trachyphonia.
RESULTS AND CONCLUSION: Through the subjective assessment by patients and analysis of vocal acoustic parameters at perioperative stage, the curative effect was satisfactory. No patients suffered from special risk and adverse reaction. ADM with perfect histocompatibility and easy operability can be applied as the new padding material to migrate the paralytic vocal cord inward.

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