Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (47): 8817-8820.doi: 10.3969/j.issn.1673-8225.2011.47.019

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Effect of surface treatment on the hemocompatibility of Ni-Ti shape memory alloy

Lu Tan1, Tian Bo2, Zhang Jiang-feng1, Wu Da-peng1, Xu Hai-bin1   

  1. 1Department of Orthopedic Surgery, the First Affiliated Hospital of Xinxiang Medical University, Xinxiang  453100, Henan Province, China
    2College of Materials Science and Metallurgy Engineering, Guizhou University, Guiyang  550003, Guizhou Province, China
  • Received:2011-07-04 Revised:2011-09-19 Online:2011-11-19 Published:2011-11-19
  • About author:Lu Tan★, Studying for master’s degree, Department of Orthopedic Surgery, the First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, Henan Province, China lutan1982@163.com

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Abstract:

BACKGROUND: Implantable Ni-Ti shape memory alloys must have better biocompatibility and biological security.
OBJECTIVE: To investigate the effect of surface treatment on the biocompatibility of Ni-Ti shape memory alloy.
METHODS: Ni-Ti shape memory alloy was randomly divided into two groups: experiment group’s materials were surface-treated by cathode electrodeposition; the others not treated were belonged to blank group. We observed the changes of material surface by scanning electron microscope and evaluated the hemolysis rate and kinetic coagulation time. The bone marrow stromal stem cells were cultured with two groups’ materials in vitro, and then we evaluated the MTT value of the two groups.
RESULTS AND CONCLUSION: After surface treatment of Ti-Ni shape memory alloy, there were many nano-size particles on its surface that formatting Ti-O. In the experimental group, the hemolysis rate was decreased and the kinetic coagulation time was prolonged. The MTT values in the experimental group were significantly higher than those in the blank group at the 2nd, 4th and 6th days after co-culture (P < 0.05). Ni-Ti shape memory alloy treated by cathode electrodeposition has the better biocompatibility and biological security.

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