Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (31): 5777-5780.doi: 10.3969/j.issn.1673-8225.2011.31.018

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Living unrelated donor kidney transplantation between spouses and living related donor kidney transplantation

Shen Bei-li，Qu Qing-shan, Yang Lei, Liang Shao-feng, Li Ming   

  1. Department of Organ Transplantation, Zhengzhou People’s Hospital, Zhengzhou   450003, Henan Province, China
  • Received:2011-03-12 Revised:2011-04-10 Online:2011-07-30 Published:2011-07-30
  • About author:Shen Bei-li, Associate chief physician, Department of Organ Transplantation, Zhengzhou People’s Hospital, Zhengzhou 450003, Henan Province, China 15903711568@139. com

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Abstract:

BACKGROUND: Living unrelated donor kidney transplantation between spouses is poorer than living related donor kidney transplantation in tissue matching, but clinical practice shows that there is no obvious difference in short-term curative effects between these two types of kidney transplantation.
OBJECTIVE: To compare the clinical curative effects between living unrelated donor kidney transplantation between spouses and living related donor kidney transplantation and summarize the clinical experience of kidney transplantation between spouses.
METHODS: A retrospective clinical data analysis was made regarding 18 patients who received kidney transplantation between spouses and 100 patients who received living related donor kidney transplantation. The clinical curative effects were compared between these two types of kidney transplantation by analyzing some indices including tissue matching before transplantation and renal function recovery, acute rejection and infection incidence at 1, 3, and 6 months.
RESULTS AND CONCLUSION: Tissue matching before transplantation was poorer in 18 patients undergoing kidney transplantation between spouses than in 100 patients undergoing living related donor kidney transplantation. Under the same transplantation proposal and immunosuppressive therapy, there was no significant difference in serum creatinine level, renal function recovery, acute rejection, and infection incidence within 6 months after transplantation between kidney transplantation between spouses and living related donor kidney transplantation (P > 0.05). These findings suggest that the clinical curative effects are similar between living unrelated donor kidney transplantation between spouses and living related donor kidney transplantation.

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