Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (20): 3759-3762.doi: 10.3969/j.issn.1673-8225.2011.20.036

Previous Articles     Next Articles

Application and value of cells co-culture in tissue engineering

Zhan Xing-wang1, Jiang Yan2, Wang Wen-liang3   

  1. 1The 8750 Hospital of Chinese People’s Armed Police Force, Mengzi  661100, Yunnan Province, China
    2College of Science, Honghe College, Mengzi  661100, Yunnan Province, China
    3Department of Orthopedics, Affiliated Hospital of College of Chinese People’s Armed Police Force, Tianjin  300162, China
  • Received:2010-12-01 Revised:2011-03-04 Online:2011-05-14 Published:2011-05-14
  • Contact: Wang Wen-liang, Doctor, Master’s supervisor, Associate chief physician, Department of Orthopedics, Affiliated Hospital of College of Chinese People’s Armed Police Force, Tianjin 300162, China Kingsouthwest2000@yahoo.com.cn
  • About author:Zhan Xing-wang★, Studying for master’s degree, the 8750 Hospital of Chinese People’s Armed Police Force, Mengzi 661100, Yunnan Province, China zhanxingwang1980@126.com
  • Supported by:

    the Natural Science Foundation of Tianjin Province, No. 10JCYBJC10800*

PDF

772

Abstract:

BACKGROUND: Cells co-culture is one kind of culture method which was established through some special culture technique in vitro. It can simulator organism intericur milieu in the greatest degree and can observe cell interaction in vitro. It is a hot topic in tissue engineering research.
OBJECTIVE: To summarize and discuss the application and value of cells co-culture in the field of tissue engineering.
METHODS: First author searched literatures from CNKI and Medline database from 2000 to 2010 using key words of “cells co-culture; bone marrow stem cells; neural stem cells; cartilage” both in Chinese or English. Co-culture cells were summarized from bone marrow stem cells, neural stem cells and cartilage cells in this paper. The application and value of cells co-culture in tissue engineering were also introduced.
RESULTS AND CONCLUSION: A total of 182 papers were searched and 30 papers were selected. The results show that most researches of co-culture are to simulation surroundings in vivo, to maintain body character, to observe cell interaction between cells to the greatest extent. These results have significant and reference value for us; however, we should further analyze and summarize the new method and technology, pay more attention to the latest trends and hotspot of cells co-culture.

CLC Number: