Abstract:

BACKGROUND: In recent years with various transplant regulations were enacted, the number of relatives kidney transplants has increased in many transplantation centers at home. At present, there is no definite restriction about the oldest age to living body kidney donor in international. Due to the extreme shortage of organ transplants, in many international transplantation centers, they are trying for the elder donor.
OBJECTIVE: To investigate the clinical effects and application prospect of the elder living kidney donors and the relatives kidney transplants.
METHODS: According to the age, 65 patients with living donor kidney transplantation were divided into 2 groups: 16 cases in the aged group (donor age ≥ 55 years) and 49 cases in the control group (donor age < 55 years). The donors of the two groups were eucrasia, functions of heart, liver, lung were perfect, and without hypertension and diabetes mellitus. The creatinine clearance rates were above 80mL/min before transplantation. The baseline datas of two groups were similar. A follow-up at 6 months after transplantation was to evaluate the renal function recovery and early complications of the two groups.
RESULTS AND CONCLUSION: The renal functions of the two groups were recovered well. There was no significant difference in early complications of acute rejection, delaying recovery of the graft function (P > 0.05). Under the lack of source of kidney, the elder donors undergo living related renal transplantation according to strict donor kidney inclusion criteria, which can obtain good therapeutic efficacy.