Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (18): 3280-3283.doi: 10.3969/j.issn.1673-8225.2011.18.013

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Several problems in brain-dead donor kidney transplantation

Wang Guang-ce, Wang Suo-gang, Zhang Zhu, Chen Zhu, Wang Wen-sheng, Cui Yong   

  1. Department of Kidney Transplantation, the Nephrosis Center, First Affiliated Hospital of Henan Traditional Medical College, Zhengzhou  450003, Henan Province, China
  • Received:2010-11-09 Revised:2011-03-22 Online:2011-04-30 Published:2011-04-30
  • About author:Wang Guang-ce, Professor, Chief physician, Master’s supervisor, Department of Kidney Transplantation, the Nephrosis Center, First Affiliated Hospital of Henan Traditional Medical College, Zhengzhou 450003, Henan Province, China wgc460@medmail.com.cn

Abstract:

BACKGROUND: Using the source of kidney up to the international standard, namely the kidney contributed freely by the cognitive death may alleviate the critical shortage in the present kidney transplant .In recent years ,the cognitive death organ contribution and the transplant have began to implant successfully in china ,but there are few reports about that.
OBJEECTIVE: To discuss the practicality of the cognitive death organ contribution kidney transplant in China and the essential condition to guarantee successful transplant. 
METHODS: Twelve patients’ experience in the cognitive death organ contribution for kidney transplant from 2007-01 to 2010-07 were summarized, including donor/for kidney’s appraisal for kidney's selecting and preservation, kidney transplant situation, transplant acceptor kidney function and complication, the time in hospital, quality of life and so on.
RESUITS AND CONCLUSION: In the 12 cases of cognitive death organ contribution kidney transplants, there were 10 patients’ kidney function recovering 2-5 days after the operation, and being discharged from hospital 14-21 days later. Two patients’ kidney function recovered slower relatively which became normal 10,15 days after transplanting separately and they were discharged from hospital on the 28th day. In 2-42 months revisiting, kidney function in 8 cases was normal, urinate protein was negative. They had been engaged in work normally and the quality of life was good; in 2 cases, urinate protein presented positive, but the kidney function was normal. One patient’s kidney function was normal, the liver function was unusual, while after treatment, it turned better; one case died of serious lung infection 3 months after operation. It indicates that the cognitive death organ contribution kidney transplant may obtain the development in China ; the cognitive death must have satisfactory blood stream dynamics, urine amount, good kidney function, who can be the ideal kidney donor; Choose the best transplant opportunity, attach importance to the systematic revisit. In this way, we can guarantee the success of cognitive death free organ contribution kidney transplants.

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