Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (29): 5327-5330.doi: 10.3969/j.issn. 2095-4344.2012.29. 002

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Nano-hydroxyapatite artificial bone serves as a spacer for fusion with the cervical spine after bone grafting

Liu Wu-yang, Mo Jian-wen, Gao Hui, Liu Hai-li, Wang Mao-yuan, He Chun-lei, Tang Wen, Ye Yong-jun   

  1. Department of Orthopedics, First Affiliated Hospital of Gannan Medical College, Ganzhou 341000, Jiangxi Province, China
  • Received:2011-12-18 Revised:2012-02-06 Online:2012-07-15 Published:2012-07-15
  • About author:Liu Wu-yang★, Master, Chief physician, Department of Orthopedics, First Affiliated Hospital of Gannan Medical College, Ganzhou 341000, Jiangxi Province, China Liuwuyang651@126.com

Abstract:

BACKGROUND: In recent years, allograft bone and coral bone have been commonly used as the spacers after double-door expansive laminoplasty, which can easily result in rejection and non-fusion.
OBJECTIVE: To verify the effect of nano-hydroxyapatite artificial bone on posterior double-door expansive laminoplasty in the cervical spine.
METHODS: Totally 46 patients undergoing posterior double-door expansive laminoplasty in the cervical spine received nano-hydroxyapatite artificial bone as the spacers. All patients were followed-up for over 3 months. Japanese Orthopaedic Association (JOA) scores before and after nano-hydroxyapatite artificial bone grafting were compared. The fusion of bone graft with the cervical spine was detected by X-ray and CT.
RESULTS AND CONCLUSION: At final follow up, JOA scores were increased from preoperative (7.9±1.9) points to (12.1±2.8) points. No patients were found cervical spine instability as well as loosening and displacement of the bone graft postoperatively. The fusion between the nano-hydroxyapatite artificial bone and spinous process was good. These findings suggest that the nano-hydroxyapatite artificial bone is an ideal bone graft substitute material and applicable to double-door expansive laminoplasty.

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