Chinese Journal of Tissue Engineering Research ›› 2026, Vol. 30 ›› Issue (5): 1320-1330.doi: 10.12307/2026.033

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A visualized analysis of research hotspots in high-frequency repetitive transcranial magnetic stimulation from the macroscopic perspective

Yang Zeyu1, Zhi Liang1, Wang Jia1, Zhang Jingyi1, Zhang Qingfang2, Wang Yulong3, Long Jianjun3   

  1. 1School of Rehabilitation Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, Shandong Province, China; 2Department of Rehabilitation, Dapeng Hospital, Shenzhen Second People’s Hospital, Shenzhen 518100, Guangdong Province, China; 3Department of Rehabilitation, Shenzhen Second People’s Hospital, Shenzhen 518035, Guangdong Province, China
  • Received:2024-12-18 Accepted:2025-02-15 Online:2026-02-18 Published:2025-06-28
  • Contact: Long Jianjun, Senior technologist, Master’s supervisor, Department of Rehabilitation, Shenzhen Second People’s Hospital, Shenzhen 518035, Guangdong Province, China
  • About author:Yang Zeyu, Master candidate, School of Rehabilitation Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, Shandong Province, China
  • Supported by:
    Medical Innovation Technology Transformation Center of Shenzhen Second People’s Hospital, No. HTHZQSWS-KCCYB-2023060 (to LJJ); Sanming Project of Medicine in Shenzhen, No. SZSM202111010 (to WYL)

Abstract: BACKGROUND: High-frequency repetitive transcranial magnetic stimulation has garnered significant attention due to its potential non-invasive benefits in modulating brain function. However, no studies have comprehensively analyzed the current research landscape and development trends of this field from a macroscopic perspective.
OBJECTIVE: To explore research hotspots, current trends, and emerging frontiers in the field of high-frequency repetitive transcranial magnetic stimulation through visualized analysis.
METHODS: Data were collected from the Web of Science Core Collection database from January 1, 2014 to November 15, 2024. CiteSpace was used for analyzing publication volume, collaborations among countries/regions, institutions and authors, citation analysis of journals and co-cited literature, as well as disciplinary distribution. Additionally, keyword co-occurrence, clustering, and burst analyses were conducted, and visualized knowledge maps were generated.
RESULTS AND CONCLUSION: A total of 860 articles were included. The publication volume of high-frequency repetitive transcranial magnetic stimulation showed an overall upward trend from 2014 to 2022, followed by a decline from 2022 to 2024. China had the highest publication volume, while Ghent University ranked as the most productive institution. Universities acted as the most high-output institutions. Chris Baeken from Ghent University was identified as the most prolific author. Collaboration among leading authors and institutions worldwide remained limited. The main research hotspots in this field were associated with keywords such as depression, stroke, neuropathic pain, and Parkinson’s disease. Burst keywords focused on mild cognitive impairment, reflecting a diversification in research directions. The overall research activity in high-frequency repetitive transcranial magnetic stimulation continues to rise, with primary focuses on its clinical applications for psychiatric and neurological disorders, as well as explorations of its underlying mechanisms. Future research may focus on optimizing treatment parameters for targeting different brain regions in clinical applications and expanding its applications and mechanisms across various domains.

Key words: high-frequency repetitive transcranial magnetic stimulation, CiteSpace, visualized analysis, Web of Science, research status, research hotspots, research trends, frontiers, engineered tissue construction

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