Chinese Journal of Tissue Engineering Research ›› 2021, Vol. 25 ›› Issue (30): 4757-4761.doi: 10.12307/2021.257

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Application of three-dimensional printing in accurate puncture vertebroplasty in fresh vertebral compression fractures

Yuan Lingli, Xu Wendi, Bai Jianzhong, Zhang Zhongchuan, Zhu Xunbing, Geng Chunhui #br#

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  1. Department of Orthopedics, Second Affiliated Hospital of Bengbu Medical College, Bengbu 233000, Anhui Province, China 
  • Received:2020-09-21 Revised:2020-09-23 Accepted:2020-11-11 Online:2021-10-28 Published:2021-07-29
  • Contact: Yuan Lingli, Department of Orthopedics, Second Affiliated Hospital of Bengbu Medical College, Bengbu 233000, Anhui Province, China
  • About author:Yuan Lingli, Master, Associate chief physician, Associate professor, Department of Orthopedics, Second Affiliated Hospital of Bengbu Medical College, Bengbu 233000, Anhui Province, China
  • Supported by:
    the Key Natural Science Project of Bengbu Medical College in 2019, No. BYKY2019134ZD (to YLL)

Abstract: BACKGROUND: At present, when clinicians use percutaneous vertebroplasty to repair vertebral compression fractures, how do they accurately operate and evenly distribute the bone cement between the injured vertebral fractures, thereby reducing the symptoms of lower back pain, for patients with vertebral compression fractures, is essential for postoperative recovery. The technology of three-dimensional (3D) printed injured vertebral body developed in recent years can provide clinical surgeons with reference for the anatomy of injured vertebra.
OBJECTIVE: To explore the clinical effect of 3D printed model of injured vertebral fracture and vertebroplasty by accurately puncturing in fresh vertebral compression fracture. 
METHODS: Sixty patients with vertebroplasty in the Second Affiliated Hospital of Bengbu Medical College from February 2019 to August 2020 were randomly divided into 3D printing group and control group. The accurately punctured vertebroplasty instructed by 3D printing model of the injured vertebra and the traditional vertebroplasty was performed respectively. The operation time, the times of fluoroscopy, the times of changing the puncture point, the amount of bone cement, and Visual Analogue Scale scores at 1 day, 1, 4 weeks and 3 months after operation were compared between the two groups. 
RESULTS AND CONCLUSION: (1) Visual Analogue Scale scores were lower in the 3D printing group than in the control group at 1 day and 1 week (P < 0.05). (2) The operation time, the times of fluoroscopy, and the times of changing the puncture point were reduced (P < 0.05); the amount of bone cement was increased (P < 0.05) in the 3D printing group compared with the control group. (3) There were two cases of local vertebral cement leakage in both groups, and there were no clinical symptoms after operation. There was no case of adjacent vertebral fractures in both groups during the follow-up. (4) The results show that the combination of 3D printing model of the injured vertebra and vertebroplasty can guide the accurate puncture of pedicle, make it easier for the puncture needle to enter the fracture area, and increase the amount of bone cement injected into the fracture area, and effectively avoid bone cement leakage, and relieve patients’ low back pain in a short time after operation.


Key words: bone, fracture, vertebral body, compression fracture, 3D printing, vertebroplasty, bone cement, model

CLC Number: